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Protein

Cytochrome c oxidase subunit 3

Gene

COXIII

Organism
Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COXIII
Encoded oniMitochondrion
OrganismiTrichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)
Taxonomic identifieri5551 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeTrichophyton

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei46 – 66HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001838681 – 269Cytochrome c oxidase subunit 3Add BLAST269

Structurei

3D structure databases

ProteinModelPortaliQ36837.
SMRiQ36837.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

CDDicd01665. Cyt_c_Oxidase_III. 1 hit.
Gene3Di1.20.120.80. 1 hit.
InterProiView protein in InterPro
IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR033945. Cyt_c_oxase_su3_dom.
IPR000298. Cyt_c_oxidase-like_su3.
IPR035973. Cyt_c_oxidase_su3-like_sf.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiView protein in Pfam
PF00510. COX3. 1 hit.
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiView protein in PROSITE
PS50253. COX3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q36837-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLYQRTNFQ SHPYHLVWPS PWPFYNSLSL FILTTSGVLT MHGFSNMYII
60 70 80 90 100
LFIAFINLVW CMTLWFRDII SEGTYLGNHT NAVQRGLNLG VGLFIASEAL
110 120 130 140 150
FFLAIFWTFF HSSLSPNVEL GAQWPPLGIK AIDPFELPLL NNIILLSSGV
160 170 180 190 200
TVNSNYHSLI QGNRKGALYG LVATILLAIV FTIFQGIEYS VSSFTISDGV
210 220 230 240 250
YGSCFYFSTG FHGFHVLIGT AFLSVGLWRL LGYHLTDHHH LGYESGILYW
260
HFVDVVWLIL YVCIYFWGY
Length:269
Mass (Da):30,599
Last modified:November 1, 1996 - v1
Checksum:i2131F595C4A23E59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X88896 Genomic DNA. Translation: CAA61357.1.
PIRiS65034.

Similar proteinsi

Entry informationi

Entry nameiCOX3_TRIRU
AccessioniPrimary (citable) accession number: Q36837
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families