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Q36837 (COX3_TRIRU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COXIII
Encoded onMitochondrion
OrganismTrichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)
Taxonomic identifier5551 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Onygenales › Arthrodermataceae › mitosporic Arthrodermataceae › Trichophyton

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183868

Regions

Transmembrane24 – 4421Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane132 – 15221Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q36837 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 2131F595C4A23E59

FASTA26930,599
        10         20         30         40         50         60 
MSLYQRTNFQ SHPYHLVWPS PWPFYNSLSL FILTTSGVLT MHGFSNMYII LFIAFINLVW 

        70         80         90        100        110        120 
CMTLWFRDII SEGTYLGNHT NAVQRGLNLG VGLFIASEAL FFLAIFWTFF HSSLSPNVEL 

       130        140        150        160        170        180 
GAQWPPLGIK AIDPFELPLL NNIILLSSGV TVNSNYHSLI QGNRKGALYG LVATILLAIV 

       190        200        210        220        230        240 
FTIFQGIEYS VSSFTISDGV YGSCFYFSTG FHGFHVLIGT AFLSVGLWRL LGYHLTDHHH 

       250        260 
LGYESGILYW HFVDVVWLIL YVCIYFWGY

« Hide

References

[1]"Organisation of the mitochondrial genome of Trichophyton rubrum. DNA sequence analysis of the ND4 gene, the ATPase subunit-6 gene, the ribosomal RNA small-subunit gene, the ND6 gene, the COXIII gene, the ATPase subunit-8 gene and six tRNA genes that correspond respectively to the tyrosine, lysine, glutamine, asparagine, isoleucine and tryptophan isoacceptors."
de Bievre C., Dujon B.
Curr. Genet. 28:553-559(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: IP 1817.89.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X88896 Genomic DNA. Translation: CAA61357.1.
PIRS65034.

3D structure databases

ProteinModelPortalQ36837.
SMRQ36837. Positions 10-268.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_TRIRU
AccessionPrimary (citable) accession number: Q36837
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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