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Q36098 (COX3_THEPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded onMitochondrion
OrganismTheileria parva (East coast fever infection agent) [Reference proteome]
Taxonomic identifier5875 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Cytochrome c oxidase subunit 3
PRO_0000232683

Regions

Transmembrane12 – 3221Helical; Potential
Transmembrane42 – 6221Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane128 – 14821Helical; Potential
Transmembrane155 – 17521Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane234 – 25421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q36098 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: A3FF61D44AA28844

FASTA25529,891
        10         20         30         40         50         60 
MRNSAQSYLK YINIINIFET LYLFYSTGLD TLEYIDSTYK NFIIMYVNQY LLYGTTLKYL 

        70         80         90        100        110        120 
SVGEFFMNSL TIFINSIREI MTSTTMVMYA IFGMFIFSEI LVFSTFIWGY FHLRLSNPIL 

       130        140        150        160        170        180 
LAELNVEAYL QISDVLNTGS ILVSIILHRV QESANFETDF FMEQLLLIGF IFLSLQNDEY 

       190        200        210        220        230        240 
SLILSYVNNY WMTLYFFILT GLHSLHVCAG GIFVLIQSYF YEGDGSQRDE EFNAGVYWHF 

       250 
VEMIWIALTM LLFLA 

« Hide

References

[1]"A 7.1 kb linear DNA molecule of Theileria parva has scrambled rDNA sequences and open reading frames for mitochondrially-encoded proteins."
Kairo A., Fairlamb A., Gobright E., Nene V.
EMBO J. 13:898-905(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Muguga.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z23263 Genomic DNA. Translation: CAA80799.1.
PIRS41690.
RefSeqYP_001994286.1. NC_011005.1.

3D structure databases

ProteinModelPortalQ36098.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6741537.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_THEPA
AccessionPrimary (citable) accession number: Q36098
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families