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Protein

Cytochrome c oxidase subunit 3

Gene

MT-CO3

Organism
Theileria parva (East coast fever infection agent)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded oniMitochondrion
OrganismiTheileria parva (East coast fever infection agent)
Taxonomic identifieri5875 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria
Proteomesi
  • UP000001949 Componenti: Mitochondrion

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Transmembranei128 – 148HelicalSequence analysisAdd BLAST21
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei234 – 254HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002326831 – 255Cytochrome c oxidase subunit 3Add BLAST255

Structurei

3D structure databases

ProteinModelPortaliQ36098.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ36098.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q36098-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNSAQSYLK YINIINIFET LYLFYSTGLD TLEYIDSTYK NFIIMYVNQY
60 70 80 90 100
LLYGTTLKYL SVGEFFMNSL TIFINSIREI MTSTTMVMYA IFGMFIFSEI
110 120 130 140 150
LVFSTFIWGY FHLRLSNPIL LAELNVEAYL QISDVLNTGS ILVSIILHRV
160 170 180 190 200
QESANFETDF FMEQLLLIGF IFLSLQNDEY SLILSYVNNY WMTLYFFILT
210 220 230 240 250
GLHSLHVCAG GIFVLIQSYF YEGDGSQRDE EFNAGVYWHF VEMIWIALTM

LLFLA
Length:255
Mass (Da):29,891
Last modified:November 1, 1996 - v1
Checksum:iA3FF61D44AA28844
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z23263 Genomic DNA. Translation: CAA80799.1.
PIRiS41690.
RefSeqiYP_001994286.1. NC_011005.1.

Genome annotation databases

GeneIDi6741537.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z23263 Genomic DNA. Translation: CAA80799.1.
PIRiS41690.
RefSeqiYP_001994286.1. NC_011005.1.

3D structure databases

ProteinModelPortaliQ36098.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6741537.

Phylogenomic databases

InParanoidiQ36098.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_THEPA
AccessioniPrimary (citable) accession number: Q36098
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.