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Q35539 (COX3_PETMA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded onMitochondrion
OrganismPetromyzon marinus (Sea lamprey)
Taxonomic identifier7757 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperoartiaPetromyzontiformesPetromyzontidaePetromyzon

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Cytochrome c oxidase subunit 3
PRO_0000183829

Regions

Transmembrane15 – 3521Helical; Potential
Transmembrane38 – 5821Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q35539 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 314B955DCC9A7B7E

FASTA26129,718
        10         20         30         40         50         60 
MSHQAHAYHM VDPSPWPLTG AGAALLMTSG LAMWFHKNSC ILMTLGLILM LLTMYQWWRD 

        70         80         90        100        110        120 
IVREGTFLGH HTSPVQQGLR YGMILFIISE VCFFAGFFWA FYHASLAPTP ELGLTWPPTG 

       130        140        150        160        170        180 
INPLNPFEVP LLNTAVLLAS GVSVTWAHHS ITEKNRTETT QALTLTVLLG LYFTALQIME 

       190        200        210        220        230        240 
YYETPFTMAD GVYGSTFFVA TGFHGLHVII GSLFLLTCLL RHLQYHFTSK HHFGFEAAAW 

       250        260 
YWHFVDVVWL FLYISIYWWG S 

« Hide

References

[1]"Complete sequence of a sea lamprey (Petromyzon marinus) mitochondrial genome: early establishment of the vertebrate genome organization."
Lee W.J., Kocher T.D.
Genetics 139:873-887(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U11880 Genomic DNA. Translation: AAB08744.1.
PIRS55010.
RefSeqNP_008154.1. NC_001626.1.

3D structure databases

ProteinModelPortalQ35539.
SMRQ35539. Positions 1-261.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSPMAT00000014129; ENSPMAP00000011437; ENSPMAG00000013102.
GeneID807805.

Organism-specific databases

CTD4514.

Phylogenomic databases

GeneTreeENSGT00390000013064.
HOVERGENHBG016686.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_PETMA
AccessionPrimary (citable) accession number: Q35539
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families