ID   NDUS3_ORYSJ             Reviewed;         190 AA.
AC   Q35322;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   08-NOV-2023, entry version 114.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3;
DE            EC=7.1.1.2;
DE   AltName: Full=NADH dehydrogenase subunit 9;
GN   Name=NAD9;
OS   Oryza sativa subsp. japonica (Rice).
OG   Mitochondrion.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND RNA EDITING.
RC   TISSUE=Leaf;
RX   PubMed=8528607; DOI=10.1093/oxfordjournals.pcp.a078858;
RA   Nishiwaki S., Nakazono M., Tsutsumi N., Hirai A.;
RT   "Structure of a gene subunit 9 of NADH dehydrogenase (nad9) in rice
RT   mitochondria and RNA editing of its transcript.";
RL   Plant Cell Physiol. 36:1135-1138(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12471441; DOI=10.1007/s00438-002-0767-1;
RA   Notsu Y., Masood S., Nishikawa T., Kubo N., Akiduki G., Nakazono M.,
RA   Hirai A., Kadowaki K.;
RT   "The complete sequence of the rice (Oryza sativa L.) mitochondrial genome:
RT   frequent DNA sequence acquisition and loss during the evolution of
RT   flowering plants.";
RL   Mol. Genet. Genomics 268:434-445(2002).
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC       NADH dehydrogenase (Complex I) that is believed to belong to the
CC       minimal assembly required for catalysis. Complex I functions in the
CC       transfer of electrons from NADH to the respiratory chain. The immediate
CC       electron acceptor for the enzyme is believed to be ubiquinone (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC         COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC   -!- SUBUNIT: Complex I is composed of about 45 different subunits. This is
CC       a component of the iron-sulfur (IP) fragment of the enzyme (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane.
CC   -!- RNA EDITING: Modified_positions=5 {ECO:0000269|PubMed:8528607}, 31
CC       {ECO:0000269|PubMed:8528607}, 38 {ECO:0000269|PubMed:8528607}, 56
CC       {ECO:0000269|PubMed:8528607}, 64 {ECO:0000269|PubMed:8528607}, 75
CC       {ECO:0000269|PubMed:8528607}, 100 {ECO:0000269|PubMed:8528607}, 104
CC       {ECO:0000269|PubMed:8528607}, 110 {ECO:0000269|PubMed:8528607}, 119
CC       {ECO:0000269|PubMed:8528607}, 123 {ECO:0000269|PubMed:8528607}, 133
CC       {ECO:0000269|PubMed:8528607};
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; D50099; BAA08794.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BA000029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; T03231; T03231.
DR   AlphaFoldDB; Q35322; -.
DR   SMR; Q35322; -.
DR   STRING; 39947.Q35322; -.
DR   PaxDb; 39947-Q35322; -.
DR   InParanoid; Q35322; -.
DR   Proteomes; UP000059680; Mitochondrion.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; ISS:Gramene.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.460.80; NADH:ubiquinone oxidoreductase, 30kDa subunit; 1.
DR   HAMAP; MF_01357; NDH1_NuoC; 1.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   NCBIfam; TIGR01961; NuoC_fam; 1.
DR   PANTHER; PTHR10884:SF14; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR10884; NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3; 1.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   SUPFAM; SSF143243; Nqo5-like; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
PE   2: Evidence at transcript level;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   NAD; Oxidoreductase; Reference proteome; Respiratory chain; RNA editing;
KW   Translocase; Transport; Ubiquinone.
FT   CHAIN           1..190
FT                   /note="NADH dehydrogenase [ubiquinone] iron-sulfur protein
FT                   3"
FT                   /id="PRO_0000118642"
SQ   SEQUENCE   190 AA;  22991 MW;  97F6A586061A2FD6 CRC64;
     MDNQFIFQYS WEILPKKWVH KMKRSEHGNR FYTNTDYLFP LLCFLKWHTY TRVQVLIDIC
     GVDYPSRKRR FEVVYNLLST RYNSRIRVQT SADEVTRISS VVSLFPSAGW WEREVWDMFG
     VSFINHPDLR RILTDYGFEG HPLRKDFPLS GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF
     ASPWEQRSDG
//