Q35322 (NDUS3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3
EC=1.6.5.3
EC=1.6.99.3

Alternative name(s):
NADH dehydrogenase subunit 9

Gene names

Name:

NAD9

Encoded on

Mitochondrion

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.
Catalytic activity	NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor.
Subunit structure	Complex I is composed of about 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme By similarity.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the complex I 30 kDa subunit family.
RNA editing	Edited at positions 5, 31, 38, 56, 64, 75, 100, 104, 110, 119, 123 and 133. Ref.1

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Coding sequence diversity	RNA editing
Ligand	NAD Ubiquinone
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrion Inferred from sequence or structural similarity Ref.1. Source: Gramene respiratory chain complex I Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC cobalt ion binding Inferred from electronic annotation. Source: EnsemblPlants/Gramene zinc ion binding Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3		PRO_0000118642

Sequences

	Sequence		Length	Mass (Da)
	Q35322 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 97F6A586061A2FD6	FASTA	190	22,991
	10 20 30 40 50 60 MDNQFIFQYS WEILPKKWVH KMKRSEHGNR FYTNTDYLFP LLCFLKWHTY TRVQVLIDIC 70 80 90 100 110 120 GVDYPSRKRR FEVVYNLLST RYNSRIRVQT SADEVTRISS VVSLFPSAGW WEREVWDMFG 130 140 150 160 170 180 VSFINHPDLR RILTDYGFEG HPLRKDFPLS GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF 190 ASPWEQRSDG

References

[1]

"Structure of a gene subunit 9 of NADH dehydrogenase (nad9) in rice mitochondria and RNA editing of its transcript." Nishiwaki S., Nakazono M., Tsutsumi N., Hirai A. Plant Cell Physiol. 36:1135-1138(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], RNA EDITING. Tissue: Leaf.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50099 Genomic DNA. Translation: BAA08794.1. Sequence problems.
PIR	T03231.
3D structure databases
ProteinModelPortal	Q35322.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	Q35322.
Phylogenomic databases
eggNOG	COG0852.
HOGENOM	HOG000009797.
Gene expression databases
ArrayExpress	Q35322.
Family and domain databases
InterPro	IPR010218. NADH_DH_suC. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. IPR020396. NADH_UbQ_OxRdtase_CS. [Graphical view]
Pfam	PF00329. Complex1_30kDa. 1 hit. [Graphical view]
ProDom	PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01961. NuoC_fam. 1 hit.
PROSITE	PS00542. COMPLEX1_30K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS3_ORYSJ

Accession

Primary (citable) accession number: Q35322

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	June 26, 2007
Last modified:	April 3, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program