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Q35242 (COX3_ENTDO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismEnteroctopus dofleini (Giant octopus) (Octopus dofleini)
Taxonomic identifier267067 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaCephalopodaColeoideaNeocoleoideaOctopodiformesOctopodaIncirrataOctopodidaeEnteroctopus

Protein attributes

Sequence length204 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›204›204Cytochrome c oxidase subunit 3
PRO_0000183814

Regions

Transmembrane12 – 3221Helical; Potential
Transmembrane56 – 7621Helical; Potential
Transmembrane101 – 12121Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane171 – 19121Helical; Potential

Experimental info

Non-terminal residue11
Non-terminal residue2041

Sequences

Sequence LengthMass (Da)Tools
Q35242 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7B3451AFC57048C6

FASTA20423,425
        10         20         30         40         50         60 
LTTGLSSWFH NYGNLLLMLG FLLMIMTMIQ WWRDIIREST FQGFHTTKVY NGLRWGMMLF 

        70         80         90        100        110        120 
IVSEICFFFA FFWAYFHSSL APNTDIGACW PPINIYPLNP FQIPLLNTAI LLSSGVSVTW 

       130        140        150        160        170        180 
AHHSLMSNKL NPAIHSMTIT ITLGFYFTFL QMMEYIEASF SISDSIYGST FFVATGFHGL 

       190        200 
HVIIGSTFLF MCLIRIIMNH FSST 

« Hide

References

[1]"The molecular phylogeny of five eastern north Pacific octopus species."
Barriga Sosa I.A., Beckenbach K., Hartwick B., Smith M.J.
Mol. Phylogenet. Evol. 4:163-174(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X83103 Genomic DNA. Translation: CAA58165.1.

3D structure databases

ProteinModelPortalQ35242.
SMRQ35242. Positions 1-203.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_ENTDO
AccessionPrimary (citable) accession number: Q35242
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families