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Q34943

- COX3_LUMTE

UniProt

Q34943 - COX3_LUMTE

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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Lumbricus terrestris (Common earthworm)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiLumbricus terrestris (Common earthworm)
Taxonomic identifieri6398 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaClitellataOligochaetaHaplotaxidaLumbricinaLumbricidaeLumbricinaeLumbricus

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Cytochrome c oxidase subunit 3PRO_0000183802Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ34943.
SMRiQ34943. Positions 6-259.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalSequence AnalysisAdd
BLAST
Transmembranei36 – 5621HelicalSequence AnalysisAdd
BLAST
Transmembranei80 – 10021HelicalSequence AnalysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence AnalysisAdd
BLAST
Transmembranei160 – 18021HelicalSequence AnalysisAdd
BLAST
Transmembranei195 – 21521HelicalSequence AnalysisAdd
BLAST
Transmembranei237 – 25721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q34943-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MIRQPFHLVE YSPWPLTSSI GAFTLAIGLA SWFHNHGFLC LTLAAFLIIV
60 70 80 90 100
SMIQWWRDVV REGTYMGHHT SLVTTGLRWG MILFITSEVM FFLAFFWAFF
110 120 130 140 150
HSSLSPTPEI GCSWPPTGIH PLNPFSVPLL NTAVLLASGV TVTWAHHSLM
160 170 180 190 200
SGKRIDATQA LILTVCLGAY FTFLQAGEYM AAPFSIADSV YGTTFFVATG
210 220 230 240 250
FHGLHVLIGS SFLAICLART WSHHFSAGHH FGFEAAAWYW HFVDVVWICL

YLCIYWWGS
Length:259
Mass (Da):29,093
Last modified:November 1, 1996 - v1
Checksum:iC974F92A9D8FF045
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U24570 Genomic DNA. Translation: AAC46867.1.
PIRiS58988.
RefSeqiNP_008241.1. NC_001673.1.

Genome annotation databases

GeneIDi807926.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U24570 Genomic DNA. Translation: AAC46867.1 .
PIRi S58988.
RefSeqi NP_008241.1. NC_001673.1.

3D structure databases

ProteinModelPortali Q34943.
SMRi Q34943. Positions 6-259.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 807926.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of the mitochondrial DNA of the annelid worm Lumbricus terrestris."
    Boore J.L., Brown W.M.
    Genetics 141:305-319(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_LUMTE
AccessioniPrimary (citable) accession number: Q34943
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3