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Q34943 (COX3_LUMTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismLumbricus terrestris (Common earthworm)
Taxonomic identifier6398 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaAnnelidaClitellataOligochaetaHaplotaxidaLumbricinaLumbricidaeLumbricinaeLumbricus

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Cytochrome c oxidase subunit 3
PRO_0000183802

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane125 – 14521Helical; Potential
Transmembrane160 – 18021Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane237 – 25721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q34943 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: C974F92A9D8FF045

FASTA25929,093
        10         20         30         40         50         60 
MIRQPFHLVE YSPWPLTSSI GAFTLAIGLA SWFHNHGFLC LTLAAFLIIV SMIQWWRDVV 

        70         80         90        100        110        120 
REGTYMGHHT SLVTTGLRWG MILFITSEVM FFLAFFWAFF HSSLSPTPEI GCSWPPTGIH 

       130        140        150        160        170        180 
PLNPFSVPLL NTAVLLASGV TVTWAHHSLM SGKRIDATQA LILTVCLGAY FTFLQAGEYM 

       190        200        210        220        230        240 
AAPFSIADSV YGTTFFVATG FHGLHVLIGS SFLAICLART WSHHFSAGHH FGFEAAAWYW 

       250 
HFVDVVWICL YLCIYWWGS 

« Hide

References

[1]"Complete sequence of the mitochondrial DNA of the annelid worm Lumbricus terrestris."
Boore J.L., Brown W.M.
Genetics 141:305-319(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U24570 Genomic DNA. Translation: AAC46867.1.
PIRS58988.
RefSeqNP_008241.1. NC_001673.1.

3D structure databases

ProteinModelPortalQ34943.
SMRQ34943. Positions 6-259.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID807926.

Organism-specific databases

CTD4514.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_LUMTE
AccessionPrimary (citable) accession number: Q34943
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families