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Q34214

- COX3_CANPA

UniProt

Q34214 - COX3_CANPA

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Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Candida parapsilosis (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Cytochrome oxidase subunit 3
Gene namesi
Name:COX3
Encoded oniMitochondrion
OrganismiCandida parapsilosis (Yeast)
Taxonomic identifieri5480 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Cytochrome c oxidase subunit 3PRO_0000183753Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ34214.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2923HelicalSequence AnalysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence AnalysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence AnalysisAdd
BLAST
Transmembranei127 – 14721HelicalSequence AnalysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence AnalysisAdd
BLAST
Transmembranei205 – 22521HelicalSequence AnalysisAdd
BLAST
Transmembranei247 – 26721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q34214-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNNVRGYLQ LHPFHLVGPS PWPIFTSFSL MDLAFSIALN SHGYMANNFY
60 70 80 90 100
IILSIITVLY SMTLWFKDII AESTYLGDHT IAVKRGLNQG FLLFVVSEIL
110 120 130 140 150
IFASLFWAYL HSAVNPTMDL GMSWPPVGID VISPAELPLL NTIILLASGV
160 170 180 190 200
TITYAHHALI NGNRANTLYG FIYSTLLIAL FVMFQFLEYK YAGFTITDGV
210 220 230 240 250
YGSTFYSLTG LHGLHMIMLT IMLVICTWRV YNYDFTNTSH VGAETTILYL
260
HVLDVIWLFI YIIVYWWGS
Length:269
Mass (Da):30,518
Last modified:November 1, 1996 - v1
Checksum:i71E15660C2E7C9CD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74411 Genomic DNA. Translation: CAE54607.1.
RefSeqiNP_943645.1. NC_005253.2.

Genome annotation databases

GeneIDi2657780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74411 Genomic DNA. Translation: CAE54607.1 .
RefSeqi NP_943645.1. NC_005253.2.

3D structure databases

ProteinModelPortali Q34214.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2657780.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "NADH dehydrogenase subunit genes in the mitochondrial DNA of yeasts."
    Nosek J., Fukuhara H.
    J. Bacteriol. 176:5622-5630(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: SR23 / CBS 7157.
  2. "Complete DNA sequence of the linear mitochondrial genome of the pathogenic yeast Candida parapsilosis."
    Nosek J., Novotna M., Hlavatovicova Z., Ussery D.W., Fajkus J., Tomaska L.
    Mol. Genet. Genomics 272:173-180(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SR23 / CBS 7157.

Entry informationi

Entry nameiCOX3_CANPA
AccessioniPrimary (citable) accession number: Q34214
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3