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Q34214 (COX3_CANPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Cytochrome oxidase subunit 3
Gene names
Name:COX3
Encoded onMitochondrion
OrganismCandida parapsilosis (Yeast)
Taxonomic identifier5480 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183753

Regions

Transmembrane7 – 2923Helical; Potential
Transmembrane51 – 7121Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q34214 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 71E15660C2E7C9CD

FASTA26930,518
        10         20         30         40         50         60 
MTNNVRGYLQ LHPFHLVGPS PWPIFTSFSL MDLAFSIALN SHGYMANNFY IILSIITVLY 

        70         80         90        100        110        120 
SMTLWFKDII AESTYLGDHT IAVKRGLNQG FLLFVVSEIL IFASLFWAYL HSAVNPTMDL 

       130        140        150        160        170        180 
GMSWPPVGID VISPAELPLL NTIILLASGV TITYAHHALI NGNRANTLYG FIYSTLLIAL 

       190        200        210        220        230        240 
FVMFQFLEYK YAGFTITDGV YGSTFYSLTG LHGLHMIMLT IMLVICTWRV YNYDFTNTSH 

       250        260 
VGAETTILYL HVLDVIWLFI YIIVYWWGS 

« Hide

References

« Hide 'large scale' references
[1]"NADH dehydrogenase subunit genes in the mitochondrial DNA of yeasts."
Nosek J., Fukuhara H.
J. Bacteriol. 176:5622-5630(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SR23 / CBS 7157.
[2]"Complete DNA sequence of the linear mitochondrial genome of the pathogenic yeast Candida parapsilosis."
Nosek J., Novotna M., Hlavatovicova Z., Ussery D.W., Fajkus J., Tomaska L.
Mol. Genet. Genomics 272:173-180(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SR23 / CBS 7157.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X74411 Genomic DNA. Translation: CAE54607.1.
RefSeqNP_943645.1. NC_005253.2.

3D structure databases

ProteinModelPortalQ34214.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2657780.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_CANPA
AccessionPrimary (citable) accession number: Q34214
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families