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Protein

NADH-ubiquinone oxidoreductase chain 5

Gene
N/A
Organism
Cepaea nemoralis (Banded wood snail)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation, UbiquinoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 5UniRule annotation (EC:1.6.5.3UniRule annotation)
Encoded oniMitochondrionImported
OrganismiCepaea nemoralis (Banded wood snail)Imported
Taxonomic identifieri28835 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraPanpulmonataEupulmonataStylommatophoraSigmurethraHelicoideaHelicidaeCepaea

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3019HelicalSequence analysisAdd
BLAST
Transmembranei51 – 7424HelicalSequence analysisAdd
BLAST
Transmembranei94 – 11926HelicalSequence analysisAdd
BLAST
Transmembranei140 – 16122HelicalSequence analysisAdd
BLAST
Transmembranei198 – 22831HelicalSequence analysisAdd
BLAST
Transmembranei240 – 26122HelicalSequence analysisAdd
BLAST
Transmembranei268 – 29023HelicalSequence analysisAdd
BLAST
Transmembranei296 – 31621HelicalSequence analysisAdd
BLAST
Transmembranei336 – 35419HelicalSequence analysisAdd
BLAST
Transmembranei374 – 39219HelicalSequence analysisAdd
BLAST
Transmembranei413 – 43523HelicalSequence analysisAdd
BLAST
Transmembranei542 – 56019HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 8942Proton_antipo_NInterPro annotationAdd
BLAST
Domaini106 – 384279Proton_antipo_MInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the complex I subunit 5 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiIPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q34177-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWFWHYQRLT SALFVFSGLS AAACFYFFLA PRIIASYDIY SQSCSIFSSS
60 70 80 90 100
AVIDATSVSF SAVVGFIASC VLMFSRHYMA SDIYYYRFTW SILLSFVISM
110 120 130 140 150
QLLIFSNSLF LLLMGWDGLV FRRLPDHMLS ERWKAARPSF LTLMVNRIGD
160 170 180 190 200
ALIMCSMFAV IFSGTALMSY FSSATRISVS FLYLVAAMTK SAQYPFSAWL
210 220 230 240 250
PAAMACPTPV SALVHPSTLV TAGVYLLVRM CLSYDMPPSL CSLLLLVGSV
260 270 280 290 300
TSLIGGVCAV YENDLKKLIA LSTLSQLGVM VFSLGLGMYS LALLHLFTHA
310 320 330 340 350
MFKALLFLAP SGVVLLHVGG TQDMRLMGSI TGKSPLLLVF LNVSSLSLAG
360 370 380 390 400
FPFLSAYYSK HAILASMWAS NSNLLAVLLM VVSMFLSSVY MFRMLKILNW
410 420 430 440 450
GVRGSSAVTA PQLSFYFYVP LILLMLGSCF AGWGLTILSA NCSSKPCANM
460 470 480 490 500
FSLCFATSPA FGHRGGYLEA LKSRWQVVLM QYYILHVPIS HTLVGHVMPE
510 520 530 540 550
CGLMFMPSSK VDLNHQHTYL RAVGFMRYCS TRSLWPLSSL QIAPFFVGAG
560
GLMAWCWYFL M
Length:561
Mass (Da):62,071
Last modified:October 19, 2011 - v3
Checksum:i415B3147069C20D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23045 Genomic DNA. Translation: AAC09516.2.
RefSeqiNP_008357.2. NC_001816.1.

Genome annotation databases

GeneIDi808122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23045 Genomic DNA. Translation: AAC09516.2.
RefSeqiNP_008357.2. NC_001816.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi808122.

Organism-specific databases

CTDi4540.

Family and domain databases

InterProiIPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete DNA sequence of the mitochondrial genome of Cepaea nemoralis (Gastropoda: Pulmonata)."
    Terrett J.A., Miles S., Thomas R.H.
    J. Mol. Evol. 42:160-168(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HepatopancreasImported.
  2. "Evolution of pulmonate gastropod mitochondrial genomes: comparisons of gene organizations of Euhadra, Cepaea and Albinaria and implications of unusual tRNA secondary structures."
    Yamazaki N., Ueshima R., Terrett J.A., Yokobori S., Kaifu M., Segawa R., Kobayashi T., Numachi K., Ueda T., Nishikawa K., Watanabe K., Thomas R.H.
    Genetics 145:749-758(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HepatopancreasImported.

Entry informationi

Entry nameiQ34177_CEPNE
AccessioniPrimary (citable) accession number: Q34177
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 19, 2011
Last modified: April 13, 2016
This is version 83 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.