Reviewed, UniProtKB/Swiss-Prot Q33DK1 (WOX3_ORYSJ)

Names and origin

Protein names

Recommended name:
    WUSCHEL-related homeobox 3
Alternative name(s):
    OsWOX3
    OsNS

Gene names

Name:	WOX3
Ordered Locus Names:	Os11g0102100, LOC_Os11g01130
AND
Ordered Locus Names:	LOC_Os12g01120
ORF Names:	OsJ_031341

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Transcription factor which may be involved in developmental processes. Seems to act as repressor of YAB5.
Subcellular location	Nucleus.
Tissue specificity	Expressed in leaf primordia, young leaves, floret meristems, floral organ primordia (except carpel primordium), stamens and carpels. Does not show polar expression pattern.
Sequence similarities	Belongs to the WUS homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	WUSCHEL-related homeobox 3		PRO_0000308637
Regions
	DNA binding	4 – 68	65	Homeobox; WUS-type
	Compositional bias	131 – 137	7	Poly-Gln

Sequences

	Sequence		Length	Mass (Da)
	Q33DK1-1 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: FB36267C29FEF655	FASTA	203	22,352
	10 20 30 40 50 60 MPQTPSTRWC PTPEQLMILE EMYRSGVRTP NAAEIQQITA HLAYYGRIEG KNVFYWFQNH 70 80 90 100 110 120 KARERQRLRR RLCARHQQQP SPPSSTVPPA PTAAAAGAVV QVHPAVMQLH HHHHHHHPYA 130 140 150 160 170 180 AAAAAQSHHL QQQQQQQAEW PAAVDYCSTA SASASATAAD MAIPPCCRPL KTLELFPTKS 190 200 TSGGLKEDCC SSSKSSSCST STN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Members of TALE and WUS subfamilies of homeodomain proteins with potentially important functions in development form dimers within each subfamily in rice." Nagasaki H., Matsuoka M., Sato Y. Genes Genet. Syst. 80:261-267(2005) [PubMed: 16284419] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Taichung 65. Tissue: Flower.
[2]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"The shoot stem cell niche in angiosperms: expression patterns of WUS orthologues in rice and maize imply major modifications in the course of mono- and dicot evolution." Nardmann J., Werr W. Mol. Biol. Evol. 23:2492-2504(2006) [PubMed: 16987950] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-68.
[5]	"A WUSCHEL-LIKE HOMEOBOX gene represses a YABBY gene expression required for rice leaf development." Dai M., Hu Y., Zhao Y., Liu H., Zhou D.-X. Plant Physiol. 144:380-390(2007) [PubMed: 17351053] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, NOMENCLATURE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB218893 mRNA. Translation: BAE48302.1. DP000010 Genomic DNA. Translation: ABA91096.1. DP000011 Genomic DNA. Translation: ABA95570.1. CM000148 Genomic DNA. Translation: EAZ17132.1. AM234748 mRNA. Translation: CAJ84140.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q33DK1.
Organism-specific databases
Gramene	Q33DK1.
Family and domain databases
InterPro	IPR001356. Homeobox. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. False negative. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

WOX3_ORYSJ

Accession

Primary (citable) accession number: Q33DK1
Secondary accession number(s): A0AAS9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	December 6, 2005
Last modified:	November 25, 2008
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)