Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

G protein-coupled receptor GPR35

Gene

Gpr35

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor GPR35Imported
Gene namesi
Name:Gpr35Imported
Synonyms:GPR35Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1309404. Gpr35.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 4123HelicalSequence analysisAdd
BLAST
Transmembranei53 – 7624HelicalSequence analysisAdd
BLAST
Transmembranei88 – 10922HelicalSequence analysisAdd
BLAST
Transmembranei130 – 15122HelicalSequence analysisAdd
BLAST
Transmembranei171 – 19626HelicalSequence analysisAdd
BLAST
Transmembranei217 – 23519HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL2390812.
GuidetoPHARMACOLOGYi102.

PTM / Processingi

Proteomic databases

PaxDbiQ33BM1.

Interactioni

Chemistry

BindingDBiQ33BM1.

Structurei

3D structure databases

ProteinModelPortaliQ33BM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 274242G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE2J. Eukaryota.
ENOG4111JSA. LUCA.
HOGENOMiHOG000112791.
HOVERGENiHBG101122.
KOiK04276.
PhylomeDBiQ33BM1.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q33BM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNTNCSILP WPAAVNHIFT IYLVLLLVLG LLLNGLALWV FCYRMHQWTE
60 70 80 90 100
TRVYMTNLAV ADVCLLCSLP FVLYSLKYST SDTPICQLSQ GIYLVNRYMS
110 120 130 140 150
ISLVTAIAVD RYVAVRHPLR ARELRSPRQA GAVCVALWVI VVTSLVLRWR
160 170 180 190 200
LGIQEGGFCF SSQNRYNFST TAFSLLGFYL PLAIVVFCSL QVVTALARRP
210 220 230 240 250
ATDVEQVEAT QKATRMVWAN LAVFIICFLP LHLILTVQVS LNLHTCAARN
260 270 280 290 300
IFSRALTITA KLSDINCCLD AICYYYMAKE FQDASLRATA SSTPHKSQDT

QSLSLT
Length:306
Mass (Da):34,283
Last modified:December 6, 2005 - v1
Checksum:iA76B4371702653AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB240684 mRNA. Translation: BAE48269.1.
RefSeqiNP_001032436.1. NM_001037359.1.
UniGeneiRn.154784.

Genome annotation databases

GeneIDi367315.
KEGGirno:367315.
UCSCiRGD:1309404. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB240684 mRNA. Translation: BAE48269.1.
RefSeqiNP_001032436.1. NM_001037359.1.
UniGeneiRn.154784.

3D structure databases

ProteinModelPortaliQ33BM1.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ33BM1.
ChEMBLiCHEMBL2390812.
GuidetoPHARMACOLOGYi102.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ33BM1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi367315.
KEGGirno:367315.
UCSCiRGD:1309404. rat.

Organism-specific databases

CTDi2859.
RGDi1309404. Gpr35.

Phylogenomic databases

eggNOGiENOG410IE2J. Eukaryota.
ENOG4111JSA. LUCA.
HOGENOMiHOG000112791.
HOVERGENiHBG101122.
KOiK04276.
PhylomeDBiQ33BM1.

Miscellaneous databases

NextBioi691101.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35."
    Taniguchi Y., Tonai-Kachi H., Shinjo K.
    FEBS Lett. 580:5003-5008(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ColonImported.

Entry informationi

Entry nameiQ33BM1_RAT
AccessioniPrimary (citable) accession number: Q33BM1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: December 9, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.