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Protein

Laccase-15

Gene

LAC15

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi96Copper 1By similarity1
Metal bindingi98Copper 2By similarity1
Metal bindingi141Copper 2By similarity1
Metal bindingi143Copper 3By similarity1
Metal bindingi503Copper 4Sequence analysis1
Metal bindingi506Copper 1By similarity1
Metal bindingi508Copper 3By similarity1
Metal bindingi565Copper 3By similarity1
Metal bindingi566Copper 4Sequence analysis1
Metal bindingi567Copper 2By similarity1
Metal bindingi571Copper 4Sequence analysis1
Metal bindingi576Copper 4Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-15 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 15
Diphenol oxidase 15
Urishiol oxidase 15
Gene namesi
Name:LAC15
Ordered Locus Names:Os10g0346300, LOC_Os10g20610
ORF Names:OSJNBa0045C13.15
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 10

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000029189930 – 599Laccase-15Add BLAST570

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi51N-linked (GlcNAc...)Sequence analysis1
Glycosylationi92N-linked (GlcNAc...)Sequence analysis1
Glycosylationi124N-linked (GlcNAc...)Sequence analysis1
Glycosylationi193N-linked (GlcNAc...)Sequence analysis1
Glycosylationi217N-linked (GlcNAc...)Sequence analysis1
Glycosylationi331N-linked (GlcNAc...)Sequence analysis1
Glycosylationi355N-linked (GlcNAc...)Sequence analysis1
Glycosylationi412N-linked (GlcNAc...)Sequence analysis1
Glycosylationi454N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ339K6.

Expressioni

Gene expression databases

GenevisibleiQ339K6. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os10g20610.1.

Structurei

3D structure databases

ProteinModelPortaliQ339K6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 162Plastocyanin-like 1Add BLAST117
Domaini173 – 328Plastocyanin-like 2Add BLAST156
Domaini444 – 586Plastocyanin-like 3Add BLAST143

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ339K6.
OMAiNEHELAD.
OrthoDBiEOG093605Y9.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 5 hits.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q339K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRCQSSRPT AAVAAVVAAV SMIIVLVSGT AIPSAAAAAA VEHTFVVSQV
60 70 80 90 100
NMTHLCKEMA FTVVNGQLPG PTIEVTEGDS VTVHVVNKSP YNLTIHWHGV
110 120 130 140 150
YQLLNCWNDG VPMITQRPIQ PNHNFTYRFN VAGQEGTLWW HAHDAFLRGT
160 170 180 190 200
VHGALIIRPR HGAASYPFPR PHREVPIIIG EWWEKDLPQV DRNMTNGYFD
210 220 230 240 250
DYSSGSTING KLGDLFNCSG VLEDGYVLDV EPGKTYLLRI INAALFSEYF
260 270 280 290 300
LKIAGHRFTV VASDANYLTP YSTDVVVIAP GETLDAIVVA DAPPSGRYYI
310 320 330 340 350
AAQPIQAPPP DTQTPEYATR GTLQYSSNSR NSSAAAMPEM PHQHDTMRSF
360 370 380 390 400
YFRGNLTAGA RLHRHGRRRV PARADESLFV TLGLGSVCRH GGASCKRGGN
410 420 430 440 450
LKESIVVANV NNVSFHIPAA AATPILEAHY YHRLHAGAGE EEEELAERPP
460 470 480 490 500
RAYNYTDQAL TPFGPEEMRL EATSRAVVTR RFRHGATVDV VFQSTAMLQG
510 520 530 540 550
DSNPMHLHGH DVFLLAQGIG IYDAARDEGK FNLVNPPRKN TVLVPNLGWA
560 570 580 590
AVRFVADNPG AWLMHCHFEF HLSMGMAAVF IVEDGPTVDT SLPPPPEDF
Length:599
Mass (Da):65,670
Last modified:December 6, 2005 - v1
Checksum:i7E10A0E08196CFDF
GO

Sequence cautioni

The sequence AAK92654 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti273T → A in AK110474 (PubMed:12869764).Curated1
Sequence conflicti311D → N in AK110474 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079634 Genomic DNA. Translation: AAK92654.1. Sequence problems.
DP000086 Genomic DNA. Translation: ABB47271.1.
AP008216 Genomic DNA. Translation: BAF26313.1.
AP014966 Genomic DNA. Translation: BAT10439.1.
AK110474 mRNA. No translation available.
RefSeqiXP_015613446.1. XM_015757960.1.
UniGeneiOs.46813.

Genome annotation databases

EnsemblPlantsiOS10T0346300-01; OS10T0346300-01; OS10G0346300.
GeneIDi4348374.
GrameneiOS10T0346300-01; OS10T0346300-01; OS10G0346300.
KEGGiosa:4348374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079634 Genomic DNA. Translation: AAK92654.1. Sequence problems.
DP000086 Genomic DNA. Translation: ABB47271.1.
AP008216 Genomic DNA. Translation: BAF26313.1.
AP014966 Genomic DNA. Translation: BAT10439.1.
AK110474 mRNA. No translation available.
RefSeqiXP_015613446.1. XM_015757960.1.
UniGeneiOs.46813.

3D structure databases

ProteinModelPortaliQ339K6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os10g20610.1.

Proteomic databases

PaxDbiQ339K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS10T0346300-01; OS10T0346300-01; OS10G0346300.
GeneIDi4348374.
GrameneiOS10T0346300-01; OS10T0346300-01; OS10G0346300.
KEGGiosa:4348374.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ339K6.
OMAiNEHELAD.
OrthoDBiEOG093605Y9.

Gene expression databases

GenevisibleiQ339K6. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 5 hits.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC15_ORYSJ
AccessioniPrimary (citable) accession number: Q339K6
Secondary accession number(s): A0A0P0XTP0, Q94HD6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 6, 2005
Last modified: November 30, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.