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Q339K6

- LAC15_ORYSJ

UniProt

Q339K6 - LAC15_ORYSJ

Protein

Laccase-15

Gene

LAC15

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (06 Dec 2005)
      Previous versions | rss
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    Functioni

    Lignin degradation and detoxification of lignin-derived products.By similarity

    Catalytic activityi

    4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

    Cofactori

    Binds 4 copper ions per monomer.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi96 – 961Copper 1By similarity
    Metal bindingi98 – 981Copper 2By similarity
    Metal bindingi141 – 1411Copper 2By similarity
    Metal bindingi143 – 1431Copper 3By similarity
    Metal bindingi503 – 5031Copper 4Sequence Analysis
    Metal bindingi506 – 5061Copper 1By similarity
    Metal bindingi508 – 5081Copper 3By similarity
    Metal bindingi565 – 5651Copper 3By similarity
    Metal bindingi566 – 5661Copper 4Sequence Analysis
    Metal bindingi567 – 5671Copper 2By similarity
    Metal bindingi571 – 5711Copper 4Sequence Analysis
    Metal bindingi576 – 5761Copper 4Sequence Analysis

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lignin catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Lignin degradation

    Keywords - Ligandi

    Copper, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Laccase-15 (EC:1.10.3.2)
    Alternative name(s):
    Benzenediol:oxygen oxidoreductase 15
    Diphenol oxidase 15
    Urishiol oxidase 15
    Gene namesi
    Name:LAC15
    Ordered Locus Names:Os10g0346300, LOC_Os10g20610
    ORF Names:OSJNBa0045C13.15
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 10

    Organism-specific databases

    GrameneiQ339K6.

    Subcellular locationi

    GO - Cellular componenti

    1. apoplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Apoplast, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2929Sequence AnalysisAdd
    BLAST
    Chaini30 – 599570Laccase-15PRO_0000291899Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi51 – 511N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi92 – 921N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi124 – 1241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi193 – 1931N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi217 – 2171N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi331 – 3311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi355 – 3551N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi412 – 4121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi454 – 4541N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi39947.LOC_Os10g20610.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ339K6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini46 – 162117Plastocyanin-like 1Add
    BLAST
    Domaini173 – 328156Plastocyanin-like 2Add
    BLAST
    Domaini444 – 586143Plastocyanin-like 3Add
    BLAST

    Sequence similaritiesi

    Belongs to the multicopper oxidase family.Curated
    Contains 3 plastocyanin-like domains.Curated

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiCOG2132.
    HOGENOMiHOG000241916.
    OMAiLEAHYYH.

    Family and domain databases

    Gene3Di2.60.40.420. 3 hits.
    InterProiIPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    [Graphical view]
    PfamiPF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49503. SSF49503. 5 hits.
    PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q339K6-1 [UniParc]FASTAAdd to Basket

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    MKRCQSSRPT AAVAAVVAAV SMIIVLVSGT AIPSAAAAAA VEHTFVVSQV    50
    NMTHLCKEMA FTVVNGQLPG PTIEVTEGDS VTVHVVNKSP YNLTIHWHGV 100
    YQLLNCWNDG VPMITQRPIQ PNHNFTYRFN VAGQEGTLWW HAHDAFLRGT 150
    VHGALIIRPR HGAASYPFPR PHREVPIIIG EWWEKDLPQV DRNMTNGYFD 200
    DYSSGSTING KLGDLFNCSG VLEDGYVLDV EPGKTYLLRI INAALFSEYF 250
    LKIAGHRFTV VASDANYLTP YSTDVVVIAP GETLDAIVVA DAPPSGRYYI 300
    AAQPIQAPPP DTQTPEYATR GTLQYSSNSR NSSAAAMPEM PHQHDTMRSF 350
    YFRGNLTAGA RLHRHGRRRV PARADESLFV TLGLGSVCRH GGASCKRGGN 400
    LKESIVVANV NNVSFHIPAA AATPILEAHY YHRLHAGAGE EEEELAERPP 450
    RAYNYTDQAL TPFGPEEMRL EATSRAVVTR RFRHGATVDV VFQSTAMLQG 500
    DSNPMHLHGH DVFLLAQGIG IYDAARDEGK FNLVNPPRKN TVLVPNLGWA 550
    AVRFVADNPG AWLMHCHFEF HLSMGMAAVF IVEDGPTVDT SLPPPPEDF 599
    Length:599
    Mass (Da):65,670
    Last modified:December 6, 2005 - v1
    Checksum:i7E10A0E08196CFDF
    GO

    Sequence cautioni

    The sequence AAK92654.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti273 – 2731T → A in AK110474. (PubMed:12869764)Curated
    Sequence conflicti311 – 3111D → N in AK110474. (PubMed:12869764)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079634 Genomic DNA. Translation: AAK92654.1. Sequence problems.
    DP000086 Genomic DNA. Translation: ABB47271.1.
    AP008216 Genomic DNA. Translation: BAF26313.1.
    AK110474 mRNA. No translation available.
    RefSeqiNP_001064399.1. NM_001070934.1.
    UniGeneiOs.46813.

    Genome annotation databases

    EnsemblPlantsiOS10T0346300-01; OS10T0346300-01; OS10G0346300.
    GeneIDi4348374.
    KEGGiosa:4348374.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079634 Genomic DNA. Translation: AAK92654.1 . Sequence problems.
    DP000086 Genomic DNA. Translation: ABB47271.1 .
    AP008216 Genomic DNA. Translation: BAF26313.1 .
    AK110474 mRNA. No translation available.
    RefSeqi NP_001064399.1. NM_001070934.1.
    UniGenei Os.46813.

    3D structure databases

    ProteinModelPortali Q339K6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 39947.LOC_Os10g20610.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS10T0346300-01 ; OS10T0346300-01 ; OS10G0346300 .
    GeneIDi 4348374.
    KEGGi osa:4348374.

    Organism-specific databases

    Gramenei Q339K6.

    Phylogenomic databases

    eggNOGi COG2132.
    HOGENOMi HOG000241916.
    OMAi LEAHYYH.

    Family and domain databases

    Gene3Di 2.60.40.420. 3 hits.
    InterProi IPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    [Graphical view ]
    Pfami PF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49503. SSF49503. 5 hits.
    PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "In-depth view of structure, activity, and evolution of rice chromosome 10."
      Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S., Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D., Oates R., Palmer M., Pries G., Gibson J., Anderson H.
      , Paradkar M., Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F., Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M., Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R., Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F., Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D., Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R., Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K., Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S., Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S., Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R., Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M., Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R., Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E., Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.
      Science 300:1566-1569(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiLAC15_ORYSJ
    AccessioniPrimary (citable) accession number: Q339K6
    Secondary accession number(s): Q94HD6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 26, 2007
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3