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Protein

Laccase-15

Gene

LAC15

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi96Copper 1By similarity1
Metal bindingi98Copper 2By similarity1
Metal bindingi141Copper 2By similarity1
Metal bindingi143Copper 3By similarity1
Metal bindingi503Copper 4Sequence analysis1
Metal bindingi506Copper 1By similarity1
Metal bindingi508Copper 3By similarity1
Metal bindingi565Copper 3By similarity1
Metal bindingi566Copper 4Sequence analysis1
Metal bindingi567Copper 2By similarity1
Metal bindingi571Copper 4Sequence analysis1
Metal bindingi576Copper 4Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-15 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 15
Diphenol oxidase 15
Urishiol oxidase 15
Gene namesi
Name:LAC15
Ordered Locus Names:Os10g0346300, LOC_Os10g20610
ORF Names:OSJNBa0045C13.15
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000029189930 – 599Laccase-15Add BLAST570

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi51N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi92N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi124N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi193N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi217N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi331N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi355N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi412N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi454N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ339K6

Expressioni

Gene expression databases

ExpressionAtlasiQ339K6 differential
GenevisibleiQ339K6 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os10g20610.1

Structurei

3D structure databases

ProteinModelPortaliQ339K6
SMRiQ339K6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 162Plastocyanin-like 1Add BLAST117
Domaini173 – 328Plastocyanin-like 2Add BLAST156
Domaini444 – 586Plastocyanin-like 3Add BLAST143

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
HOGENOMiHOG000241916
InParanoidiQ339K6
OMAiNYLTPYT
OrthoDBiEOG093605Y9

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
cd13897 CuRO_3_LCC_plant, 1 hit
Gene3Di2.60.40.420, 3 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR034289 CuRO_3_LCC
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 5 hits
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q339K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRCQSSRPT AAVAAVVAAV SMIIVLVSGT AIPSAAAAAA VEHTFVVSQV
60 70 80 90 100
NMTHLCKEMA FTVVNGQLPG PTIEVTEGDS VTVHVVNKSP YNLTIHWHGV
110 120 130 140 150
YQLLNCWNDG VPMITQRPIQ PNHNFTYRFN VAGQEGTLWW HAHDAFLRGT
160 170 180 190 200
VHGALIIRPR HGAASYPFPR PHREVPIIIG EWWEKDLPQV DRNMTNGYFD
210 220 230 240 250
DYSSGSTING KLGDLFNCSG VLEDGYVLDV EPGKTYLLRI INAALFSEYF
260 270 280 290 300
LKIAGHRFTV VASDANYLTP YSTDVVVIAP GETLDAIVVA DAPPSGRYYI
310 320 330 340 350
AAQPIQAPPP DTQTPEYATR GTLQYSSNSR NSSAAAMPEM PHQHDTMRSF
360 370 380 390 400
YFRGNLTAGA RLHRHGRRRV PARADESLFV TLGLGSVCRH GGASCKRGGN
410 420 430 440 450
LKESIVVANV NNVSFHIPAA AATPILEAHY YHRLHAGAGE EEEELAERPP
460 470 480 490 500
RAYNYTDQAL TPFGPEEMRL EATSRAVVTR RFRHGATVDV VFQSTAMLQG
510 520 530 540 550
DSNPMHLHGH DVFLLAQGIG IYDAARDEGK FNLVNPPRKN TVLVPNLGWA
560 570 580 590
AVRFVADNPG AWLMHCHFEF HLSMGMAAVF IVEDGPTVDT SLPPPPEDF
Length:599
Mass (Da):65,670
Last modified:December 6, 2005 - v1
Checksum:i7E10A0E08196CFDF
GO

Sequence cautioni

The sequence AAK92654 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti273T → A in AK110474 (PubMed:12869764).Curated1
Sequence conflicti311D → N in AK110474 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079634 Genomic DNA Translation: AAK92654.1 Sequence problems.
DP000086 Genomic DNA Translation: ABB47271.1
AP008216 Genomic DNA Translation: BAF26313.1
AP014966 Genomic DNA Translation: BAT10439.1
AK110474 mRNA No translation available.
RefSeqiXP_015613446.1, XM_015757960.1
UniGeneiOs.46813

Genome annotation databases

EnsemblPlantsiOs10t0346300-01; Os10t0346300-01; Os10g0346300
GeneIDi4348374
GrameneiOs10t0346300-01; Os10t0346300-01; Os10g0346300
KEGGiosa:4348374

Similar proteinsi

Entry informationi

Entry nameiLAC15_ORYSJ
AccessioniPrimary (citable) accession number: Q339K6
Secondary accession number(s): A0A0P0XTP0, Q94HD6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 6, 2005
Last modified: June 20, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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