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Protein

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3

Gene

NAD9

Organism
Beta trigyna (Caucasian wild beet)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Respiratory chain, Transport
LigandNAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
NADH dehydrogenase subunit 9
Gene namesi
Name:NAD9
Encoded oniMitochondrion
OrganismiBeta trigyna (Caucasian wild beet)
Taxonomic identifieri19769 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesChenopodiaceaeBetoideaeBeta

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001186381 – 192NADH dehydrogenase [ubiquinone] iron-sulfur protein 3Add BLAST192

Proteomic databases

PRIDEiQ33994.

Interactioni

Subunit structurei

Complex I is composed of about 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ33994.
SMRiQ33994.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC. 1 hit.
InterProiView protein in InterPro
IPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
PfamiView protein in Pfam
PF00329. Complex1_30kDa. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiView protein in PROSITE
PS00542. COMPLEX1_30K. 1 hit.

Sequencei

Sequence statusi: Complete.

Q33994-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNQFIFKYS WETLPKKWVK KIEKSEHGNR FDTNTDYLFQ LLCFLKLHTY
60 70 80 90 100
TRFQVLIDIC GVDYPSRKRR FEVVYNLLST RYNSRIRLQT SADEVTRISS
110 120 130 140 150
VVSLFPSAGW WEREVWDMFG VSFINHPDLR RILTDYGFEG HPLRKDFPLS
160 170 180 190
GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF ASPWEQRNGN EG
Length:192
Mass (Da):23,109
Last modified:November 1, 1997 - v1
Checksum:i12C3F3F5AA32A925
GO

RNA editingi

Edited at positions 31, 38, 100, 110 and 123.By similarity

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38017 Genomic DNA. Translation: BAA07214.1. Sequence problems.

Keywords - Coding sequence diversityi

RNA editing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38017 Genomic DNA. Translation: BAA07214.1. Sequence problems.

3D structure databases

ProteinModelPortaliQ33994.
SMRiQ33994.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ33994.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC. 1 hit.
InterProiView protein in InterPro
IPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
PfamiView protein in Pfam
PF00329. Complex1_30kDa. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiView protein in PROSITE
PS00542. COMPLEX1_30K. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNDUS3_BETTR
AccessioniPrimary (citable) accession number: Q33994
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 15, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.