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Q338B9 (GCN5_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Histone acetyltransferase GCN5

EC=2.3.1.48
Gene names
Name:GCN5
Ordered Locus Names:Os10g0415900, LOC_Os10g28040
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length511 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Acetylates histone H3. Acetylation of histones gives a specific tag for epigenetic transcription activation. Operates in concert with certain DNA-binding transcriptional activators. Acts via the formation of large multiprotein complexes that modify the chromatin By similarity.

Catalytic activity

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the acetyltransferase family. GCN5 subfamily.

Contains 1 bromo domain.

Contains 1 N-acetyltransferase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 511511Histone acetyltransferase GCN5
PRO_0000269749

Regions

Domain168 – 315148N-acetyltransferase
Domain415 – 48672Bromo
Compositional bias8 – 6760Ser-rich
Compositional bias68 – 736Poly-Asp
Compositional bias104 – 12421Ala-rich

Sequences

Sequence LengthMass (Da)Tools
Q338B9 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: A506C27F8D96D673

FASTA51156,685
        10         20         30         40         50         60 
MDGLAAPSPS HSGATSGGGA SHRKRKLPPS SLSDATADED DDTTAPSSPS TSPSSPSRPS 

        70         80         90        100        110        120 
SPSSSHSDDD DDDSLHTFTA ARLDGAPPSS SGRPPKPESS TVSAAAAAAA AAAAPKPDSA 

       130        140        150        160        170        180 
SAAAGDGKED PKGLFTDNIQ TSGAYSAREE GLKREEEAGR LKFLCYSNDG VDEHMIWLVG 

       190        200        210        220        230        240 
LKNIFARQLP NMPKEYIVRL VMDRTHKSMM VIRNNIVVGG ITYRPYTSQK FGEIAFCAIT 

       250        260        270        280        290        300 
ADEQVKGYGT RLMNHLKQHA RDADGLTHFL TYADNNAVGY FVKQGFTKEI TLDKERWQGY 

       310        320        330        340        350        360 
IKDYDGGILM ECRIDQKLPY VDLATMIRRQ RQAIDEKIRE LSNCHIVYSG IDFQKKEAGI 

       370        380        390        400        410        420 
PRRTMKPEDI QGLREAGWTP DQWGHSKSRS AFSPDYSTYR QQLTNLMRSL LKNMNEHPDA 

       430        440        450        460        470        480 
WPFKEPVDSR DVPDYYDIIK DPIDLKTMSK RVESEQYYVT LEMFVADMKR MFSNAKTYNS 

       490        500        510 
PDTIYYKCAS RLESFFSNKV ASQLAQASTK N 

« Hide

References

« Hide 'large scale' references
[1]"In-depth view of structure, activity, and evolution of rice chromosome 10."
Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S., Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D., Oates R., Palmer M., Pries G., Gibson J., Anderson H. expand/collapse author list , Paradkar M., Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F., Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M., Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R., Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F., Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D., Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R., Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K., Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S., Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S., Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R., Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M., Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R., Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E., Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.
Science 300:1566-1569(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DP000086 Genomic DNA. Translation: ABB47615.1.
AP008216 Genomic DNA. Translation: BAF26518.1.
AK111779 mRNA. No translation available.
RefSeqNP_001064604.1. NM_001071139.1.
UniGeneOs.21782.

3D structure databases

ProteinModelPortalQ338B9.
SMRQ338B9. Positions 160-322.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os10g28040.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS10T0415900-01; OS10T0415900-01; OS10G0415900.
GeneID4348629.
KEGGosa:4348629.

Organism-specific databases

GrameneQ338B9.

Phylogenomic databases

eggNOGCOG5076.
HOGENOMHOG000192257.
KOK06062.
OMAMVIRNNI.

Family and domain databases

Gene3D1.20.920.10. 1 hit.
3.40.630.30. 1 hit.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR000182. GNAT_dom.
[Graphical view]
PfamPF00583. Acetyltransf_1. 1 hit.
PF00439. Bromodomain. 1 hit.
[Graphical view]
PRINTSPR00503. BROMODOMAIN.
SMARTSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMSSF47370. SSF47370. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCN5_ORYSJ
AccessionPrimary (citable) accession number: Q338B9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 6, 2005
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations