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Q33824

- COX3_PATPE

UniProt

Q33824 - COX3_PATPE

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Protein
Cytochrome c oxidase subunit 3
Gene
COIII
Organism
Patiria pectinifera (Starfish) (Asterina pectinifera)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiPatiria pectinifera (Starfish) (Asterina pectinifera)
Taxonomic identifieri7594 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaAsterozoaAsteroideaValvataceaValvatidaAsterinidaePatiria

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421Helical; Reviewed prediction
Add
BLAST
Transmembranei41 – 6121Helical; Reviewed prediction
Add
BLAST
Transmembranei81 – 10121Helical; Reviewed prediction
Add
BLAST
Transmembranei126 – 14621Helical; Reviewed prediction
Add
BLAST
Transmembranei158 – 17821Helical; Reviewed prediction
Add
BLAST
Transmembranei196 – 21621Helical; Reviewed prediction
Add
BLAST
Transmembranei238 – 25821Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260Cytochrome c oxidase subunit 3
PRO_0000183743Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ33824.
SMRiQ33824. Positions 1-260.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q33824-1 [UniParc]FASTAAdd to Basket

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MTHQHPYHLV DQSPWPLTGA ISALMMTSGL ILWFHTNSNH LLLAGTILLL    50
LTVINWWRDV IREATFQGSH TLPVNTGLRY GMILFITSEV CFFFAFFWAF 100
FHSSLAPTVE LGVSWPPTGI SPINPFLVPL LNTAVLLSSG VTVTWAHHSI 150
LTQNRTEAIQ GLFLTVILGI YFTGLQAWEY YDSPFTIADS VYGSSFFVAT 200
GFHGLHVLIG TTFLFICFLR LITFHFSNNH HFGFEAAAWY WHFVDVVWLF 250
LYICICWWGS 260
Length:260
Mass (Da):29,587
Last modified:May 30, 2000 - v2
Checksum:iEF72F6E603E4053B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D16387 Genomic DNA. Translation: BAA03885.2.
M17619 Genomic DNA. Translation: AAA65514.2.
PIRiS70589.
RefSeqiNP_008160.1. NC_001627.1.

Genome annotation databases

GeneIDi807818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D16387 Genomic DNA. Translation: BAA03885.2 .
M17619 Genomic DNA. Translation: AAA65514.2 .
PIRi S70589.
RefSeqi NP_008160.1. NC_001627.1.

3D structure databases

ProteinModelPortali Q33824.
SMRi Q33824. Positions 1-260.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 807818.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence and gene organization of the starfish Asterina pectinifera mitochondrial genome."
    Asakawa S., Himeno H., Miura K., Watanabe K.
    Genetics 140:1047-1060(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Ovary.
  2. "Unusual genetic codes and a novel gene structure for tRNA(AGYSer) in starfish mitochondrial DNA."
    Himeno H., Masaki H., Kawai T., Ohta T., Kumagai I., Miura K., Watanabe K.
    Gene 56:219-230(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 193-260.

Entry informationi

Entry nameiCOX3_PATPE
AccessioniPrimary (citable) accession number: Q33824
Secondary accession number(s): P11958
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: September 3, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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