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Q33824 (COX3_PATPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismPatiria pectinifera (Starfish) (Asterina pectinifera)
Taxonomic identifier7594 [NCBI]
Taxonomic lineageEukaryotaMetazoaEchinodermataEleutherozoaAsterozoaAsteroideaValvataceaValvatidaAsterinidaePatiria

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 260260Cytochrome c oxidase subunit 3
PRO_0000183743

Regions

Transmembrane14 – 3421Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane126 – 14621Helical; Potential
Transmembrane158 – 17821Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane238 – 25821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q33824 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: EF72F6E603E4053B

FASTA26029,587
        10         20         30         40         50         60 
MTHQHPYHLV DQSPWPLTGA ISALMMTSGL ILWFHTNSNH LLLAGTILLL LTVINWWRDV 

        70         80         90        100        110        120 
IREATFQGSH TLPVNTGLRY GMILFITSEV CFFFAFFWAF FHSSLAPTVE LGVSWPPTGI 

       130        140        150        160        170        180 
SPINPFLVPL LNTAVLLSSG VTVTWAHHSI LTQNRTEAIQ GLFLTVILGI YFTGLQAWEY 

       190        200        210        220        230        240 
YDSPFTIADS VYGSSFFVAT GFHGLHVLIG TTFLFICFLR LITFHFSNNH HFGFEAAAWY 

       250        260 
WHFVDVVWLF LYICICWWGS 

« Hide

References

[1]"Nucleotide sequence and gene organization of the starfish Asterina pectinifera mitochondrial genome."
Asakawa S., Himeno H., Miura K., Watanabe K.
Genetics 140:1047-1060(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Ovary.
[2]"Unusual genetic codes and a novel gene structure for tRNA(AGYSer) in starfish mitochondrial DNA."
Himeno H., Masaki H., Kawai T., Ohta T., Kumagai I., Miura K., Watanabe K.
Gene 56:219-230(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 193-260.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D16387 Genomic DNA. Translation: BAA03885.2.
M17619 Genomic DNA. Translation: AAA65514.2.
PIRS70589.
RefSeqNP_008160.1. NC_001627.1.

3D structure databases

ProteinModelPortalQ33824.
SMRQ33824. Positions 1-260.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID807818.

Organism-specific databases

CTD4514.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_PATPE
AccessionPrimary (citable) accession number: Q33824
Secondary accession number(s): P11958
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: May 14, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families