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Q33752 (COX3_ARBLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismArbacia lixula (Black urchin) (Echinus lixula)
Taxonomic identifier7640 [NCBI]
Taxonomic lineageEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaArbacoidaArbaciidaeArbacia

Protein attributes

Sequence length109 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 109›109Cytochrome c oxidase subunit 3
PRO_0000183738

Regions

Transmembrane7 – 2721Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane87 – 10721Helical; Potential

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q33752 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3B4617A8F7512963

FASTA10912,511
        10         20         30         40         50         60 
AGNRTEAVQA LFLTVALGIY FTILQAWEYY DSPFTIADSV YGSTFFVATG FHGLHVINST 

        70         80         90        100 
TFLLVCLFRL INFHFSAHHH FGFEAAAWYW DFVDVVVAFS LYMHIWWGS 

« Hide

References

[1]"Mitochondrial DNA in the sea urchin Arbacia lixula: evolutionary inferences from nucleotide sequence analysis."
de Giorgi C., Lanave C., Musci M.D., Saccone C.
Mol. Biol. Evol. 8:515-529(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M74839 Genomic DNA. Translation: AAA98044.1.

3D structure databases

ProteinModelPortalQ33752.
SMRQ33752. Positions 2-109.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_ARBLI
AccessionPrimary (citable) accession number: Q33752
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families