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Q336M2

- CDKE1_ORYSJ

UniProt

Q336M2 - CDKE1_ORYSJ

Protein

Cyclin-dependent kinase E-1

Gene

CDKE-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (22 Aug 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.
    ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei59 – 591ATPPROSITE-ProRule annotation
    Active sitei158 – 1581Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi25 – 339ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
    3. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin-dependent kinase E-1 (EC:2.7.11.22, EC:2.7.11.23)
    Short name:
    CDKE;1
    Gene namesi
    Name:CDKE-1
    Ordered Locus Names:Os10g0580300, LOC_Os10g42950
    ORF Names:OSJNBa0056G17.11
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 10

    Organism-specific databases

    GrameneiQ336M2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Cyclin-dependent kinase E-1PRO_0000296104Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei29 – 291PhosphothreonineBy similarity
    Modified residuei30 – 301PhosphotyrosineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PRIDEiQ336M2.

    Expressioni

    Inductioni

    By auxin. Down-regulated by cytokinin.1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliQ336M2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini19 – 337319Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000233024.
    KOiK02208.
    OMAiKWPTLAN.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q336M2-1 [UniParc]FASTAAdd to Basket

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    MGDGRVGGGT NRPAWLQQYE LVGKIGEGTY GLVFLARLKQ SHPHAAAGVG    50
    RRGSPIAIKK FKQSKEGDGV SPTAIREIML LREINHENVV KLVNVHINHA 100
    DMSLYLAFDY AEHDLYEIIR HHREKLNLPI NPYTVKSLLW QLLNGLNYLH 150
    SNWIIHRDLK PSNILVMGEG EEHGIIKIAD FGLARIYQAP LKPLSDNGVV 200
    VTIWYRAPEL LLGAKHYTSA VDMWAVGCIF AELLTLKPLF QGVEAKATPN 250
    PFQLDQLDKI FKVLGHPTVE KWPTLANLPC WQNDQQHIQG HKYENTGLHN 300
    IVHLPQKSPA FDLLSKMLEY DPRKRITAAQ ALEHEYFRMD PLPGRNALLP 350
    SQAGEKIVQY PVRPVDTTTD FEGTTSLQPT QAPSGNAAPG NQSVVPRPIP 400
    RQMQQPMVGM SRMGGTNMAA FGAAPQGGIA GMNPGNIPMQ RGAGAQSHPH 450
    QLRRKADQGM GMQNPGYPTQ QKRRF 475
    Length:475
    Mass (Da):52,808
    Last modified:August 22, 2006 - v2
    Checksum:iD7CD5C959C39C349
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018727 Genomic DNA. Translation: AAG46164.1.
    DP000086 Genomic DNA. Translation: ABB48043.2.
    AP008216 Genomic DNA. Translation: BAF27349.1.
    AK066824 mRNA. No translation available.
    RefSeqiNP_001065512.1. NM_001072044.1.
    UniGeneiOs.2989.

    Genome annotation databases

    EnsemblPlantsiOS10T0580300-01; OS10T0580300-01; OS10G0580300.
    GeneIDi4349519.
    KEGGiosa:4349519.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018727 Genomic DNA. Translation: AAG46164.1 .
    DP000086 Genomic DNA. Translation: ABB48043.2 .
    AP008216 Genomic DNA. Translation: BAF27349.1 .
    AK066824 mRNA. No translation available.
    RefSeqi NP_001065512.1. NM_001072044.1.
    UniGenei Os.2989.

    3D structure databases

    ProteinModelPortali Q336M2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q336M2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS10T0580300-01 ; OS10T0580300-01 ; OS10G0580300 .
    GeneIDi 4349519.
    KEGGi osa:4349519.

    Organism-specific databases

    Gramenei Q336M2.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000233024.
    KOi K02208.
    OMAi KWPTLAN.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "In-depth view of structure, activity, and evolution of rice chromosome 10."
      Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S., Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D., Oates R., Palmer M., Pries G., Gibson J., Anderson H.
      , Paradkar M., Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F., Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M., Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R., Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F., Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D., Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R., Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K., Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S., Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S., Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R., Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M., Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R., Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E., Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.
      Science 300:1566-1569(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.
    5. "Genome-wide identification and expression analysis of rice cell cycle genes."
      Guo J., Song J., Wang F., Zhang X.S.
      Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, GENE FAMILY.

    Entry informationi

    Entry nameiCDKE1_ORYSJ
    AccessioniPrimary (citable) accession number: Q336M2
    Secondary accession number(s): Q9FRN5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: August 22, 2006
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3