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Q336M2

- CDKE1_ORYSJ

UniProt

Q336M2 - CDKE1_ORYSJ

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Protein

Cyclin-dependent kinase E-1

Gene
CDKE-1, Os10g0580300, LOC_Os10g42950, OSJNBa0056G17.11
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei59 – 591ATP By similarity
Active sitei158 – 1581Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi25 – 339ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
  3. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase E-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKE;1
Gene namesi
Name:CDKE-1
Ordered Locus Names:Os10g0580300, LOC_Os10g42950
ORF Names:OSJNBa0056G17.11
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 10

Organism-specific databases

GrameneiQ336M2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Cyclin-dependent kinase E-1PRO_0000296104Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei29 – 291Phosphothreonine By similarity
Modified residuei30 – 301Phosphotyrosine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ336M2.

Expressioni

Inductioni

By auxin. Down-regulated by cytokinin.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ336M2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 337319Protein kinaseAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
KOiK02208.
OMAiKWPTLAN.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q336M2-1 [UniParc]FASTAAdd to Basket

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MGDGRVGGGT NRPAWLQQYE LVGKIGEGTY GLVFLARLKQ SHPHAAAGVG    50
RRGSPIAIKK FKQSKEGDGV SPTAIREIML LREINHENVV KLVNVHINHA 100
DMSLYLAFDY AEHDLYEIIR HHREKLNLPI NPYTVKSLLW QLLNGLNYLH 150
SNWIIHRDLK PSNILVMGEG EEHGIIKIAD FGLARIYQAP LKPLSDNGVV 200
VTIWYRAPEL LLGAKHYTSA VDMWAVGCIF AELLTLKPLF QGVEAKATPN 250
PFQLDQLDKI FKVLGHPTVE KWPTLANLPC WQNDQQHIQG HKYENTGLHN 300
IVHLPQKSPA FDLLSKMLEY DPRKRITAAQ ALEHEYFRMD PLPGRNALLP 350
SQAGEKIVQY PVRPVDTTTD FEGTTSLQPT QAPSGNAAPG NQSVVPRPIP 400
RQMQQPMVGM SRMGGTNMAA FGAAPQGGIA GMNPGNIPMQ RGAGAQSHPH 450
QLRRKADQGM GMQNPGYPTQ QKRRF 475
Length:475
Mass (Da):52,808
Last modified:August 22, 2006 - v2
Checksum:iD7CD5C959C39C349
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC018727 Genomic DNA. Translation: AAG46164.1.
DP000086 Genomic DNA. Translation: ABB48043.2.
AP008216 Genomic DNA. Translation: BAF27349.1.
AK066824 mRNA. No translation available.
RefSeqiNP_001065512.1. NM_001072044.1.
UniGeneiOs.2989.

Genome annotation databases

EnsemblPlantsiOS10T0580300-01; OS10T0580300-01; OS10G0580300.
GeneIDi4349519.
KEGGiosa:4349519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC018727 Genomic DNA. Translation: AAG46164.1 .
DP000086 Genomic DNA. Translation: ABB48043.2 .
AP008216 Genomic DNA. Translation: BAF27349.1 .
AK066824 mRNA. No translation available.
RefSeqi NP_001065512.1. NM_001072044.1.
UniGenei Os.2989.

3D structure databases

ProteinModelPortali Q336M2.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q336M2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS10T0580300-01 ; OS10T0580300-01 ; OS10G0580300 .
GeneIDi 4349519.
KEGGi osa:4349519.

Organism-specific databases

Gramenei Q336M2.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
KOi K02208.
OMAi KWPTLAN.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "In-depth view of structure, activity, and evolution of rice chromosome 10."
    Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S., Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D., Oates R., Palmer M., Pries G., Gibson J., Anderson H.
    , Paradkar M., Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F., Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M., Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R., Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F., Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D., Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R., Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K., Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S., Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S., Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R., Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M., Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R., Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E., Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.
    Science 300:1566-1569(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  5. "Genome-wide identification and expression analysis of rice cell cycle genes."
    Guo J., Song J., Wang F., Zhang X.S.
    Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, GENE FAMILY.

Entry informationi

Entry nameiCDKE1_ORYSJ
AccessioniPrimary (citable) accession number: Q336M2
Secondary accession number(s): Q9FRN5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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