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Protein

Elongation factor Tu, apicoplast

Gene

tufA

Organism
Eimeria tenella (Coccidian parasite)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPBy similarity8
Nucleotide bindingi81 – 85GTPBy similarity5
Nucleotide bindingi136 – 139GTPBy similarity4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu, apicoplast
Short name:
EF-Tu
Gene namesi
Name:tufA
Synonyms:tuf
Encoded oniPlastid; Apicoplast
OrganismiEimeria tenella (Coccidian parasite)
Taxonomic identifieri5802 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaEimeriidaeEimeria

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apicoplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003375961 – 403Elongation factor Tu, apicoplastAdd BLAST403

Structurei

3D structure databases

ProteinModelPortaliQ33451.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 210tr-type GAdd BLAST201

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni60 – 64G2By similarity5
Regioni81 – 84G3By similarity4
Regioni136 – 139G4By similarity4
Regioni174 – 176G5By similarity3

Sequence similaritiesi

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q33451-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKFFEKTK THLNIGTIGH VDHGKTTLTA AITSYLSKIN NTKAKSYSEI
60 70 80 90 100
DSAPEEKARG ITINTSHIEY ETNLRHYAHI DCPGHADYIK NMITGAAQMD
110 120 130 140 150
GAILVVSATD GPMPQTREHL LLAKQVGVPN IIVFLNKIDM VEDNELLELV
160 170 180 190 200
ELEVRELLDI YEYNGDSTSI IKGSALKALE YIEKNDLNNK WVKNLKNLIE
210 220 230 240 250
ALDKSIPEPK RDINKPFLLS IEDIFSITGR GTVVTGKIER GKVKLNDTVD
260 270 280 290 300
ILGFNLLKTT TVTGIEMFQK ILNTAEAGDN VGILLRGIQK NEVRRGMVLA
310 320 330 340 350
KPLSILTYSK FDAEVYILSS SEGGRKKPFF EGYKPQFYFY TTDVTGTIEF
360 370 380 390 400
LRNPEKPEMI LPGDKVKLRI SLMYSIALEK GMRFAIREGG KTIGAGIIID

LIN
Length:403
Mass (Da):44,971
Last modified:November 1, 1996 - v1
Checksum:i183FB831905BA697
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89446 Genomic DNA. Translation: CAA61615.1.
Y12332 Genomic DNA. Translation: CAA73000.1.
AY217738 Genomic DNA. Translation: AAO40237.1.
PIRiS57945.
RefSeqiNP_852636.1. NC_004823.1.

Genome annotation databases

GeneIDi1263692.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89446 Genomic DNA. Translation: CAA61615.1.
Y12332 Genomic DNA. Translation: CAA73000.1.
AY217738 Genomic DNA. Translation: AAO40237.1.
PIRiS57945.
RefSeqiNP_852636.1. NC_004823.1.

3D structure databases

ProteinModelPortaliQ33451.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1263692.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU_EIMTE
AccessioniPrimary (citable) accession number: Q33451
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 1, 1996
Last modified: October 5, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.