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Protein

Beta-defensin 14

Gene

Defb14

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Has antibacterial activity.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Defensin

Enzyme and pathway databases

ReactomeiR-RNO-1461957 Beta defensins
R-RNO-1461973 Defensins

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-defensin 14
Short name:
BD-14
Alternative name(s):
Defensin, beta 14
Gene namesi
Name:Defb14
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1561378 Defb14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000035269923 – 67Beta-defensin 14Add BLAST45

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 62By similarity
Disulfide bondi40 ↔ 55By similarity
Disulfide bondi45 ↔ 63By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ32ZH7
PRIDEiQ32ZH7

Expressioni

Gene expression databases

BgeeiENSRNOG00000032304

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000048330

Structurei

3D structure databases

ProteinModelPortaliQ32ZH7
SMRiQ32ZH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-defensin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JFYR Eukaryota
ENOG411134U LUCA
GeneTreeiENSGT00530000064280
HOGENOMiHOG000015465
HOVERGENiHBG004834
InParanoidiQ32ZH7
OMAiIRGGRCA
PhylomeDBiQ32ZH7

Family and domain databases

InterProiView protein in InterPro
IPR001855 Defensin_beta-typ
PfamiView protein in Pfam
PF00711 Defensin_beta, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q32ZH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLHYLLFVF LILFLVPAPG DTFIPKSLRR FFCRVRGGRC AILNCLGKEE
60
QIGRCSNRGQ KCCRKKK
Length:67
Mass (Da):7,803
Last modified:December 6, 2005 - v1
Checksum:i635E5983B9A77734
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY621346 mRNA Translation: AAT51885.1
RefSeqiNP_001032593.1, NM_001037504.1
XP_006253434.1, XM_006253372.2
XP_017455730.1, XM_017600241.1
UniGeneiRn.160439

Genome annotation databases

EnsembliENSRNOT00000048414; ENSRNOP00000048330; ENSRNOG00000032304
GeneIDi641627
KEGGirno:641627
UCSCiRGD:1561378 rat

Similar proteinsi

Entry informationi

Entry nameiDFB14_RAT
AccessioniPrimary (citable) accession number: Q32ZH7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: December 6, 2005
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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