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Q32ZG8

- Q32ZG8_RAT

UniProt

Q32ZG8 - Q32ZG8_RAT

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Protein

Beta-defensin

Gene
Defb24, rCG_37392
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Has antibacterial activity By similarity.UniRule annotation

GO - Biological processi

  1. defense response to bacterium Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

AntibioticUniRule annotationSAAS annotations, Antimicrobial, DefensinUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-defensinUniRule annotation
Gene namesi
Name:Defb24Imported
ORF Names:rCG_37392Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 3

Organism-specific databases

RGDi1559541. Defb24.

Subcellular locationi

Secreted By similarity UniRule annotation

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriQ32ZG8.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000052276.

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-defensin family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiNOG87541.
GeneTreeiENSGT00510000050451.
HOGENOMiHOG000112157.
HOVERGENiHBG107794.
InParanoidiQ32ZG8.
OMAiVEDNTNW.
OrthoDBiEOG7DZ8NX.

Family and domain databases

InterProiIPR025933. Beta_defensin.
[Graphical view]
PfamiPF13841. Defensin_beta_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q32ZG8-1 [UniParc]FASTAAdd to Basket

« Hide

MKLVLLLLAI FVTTELVMSG KNPTLQCMGN RGFCRPSCKK GEQAYFYCRT   50
YQICCLQSHV RISLTGVEDN TNWSYEKHWP RIP 83
Length:83
Mass (Da):9,618
Last modified:December 6, 2005 - v1
Checksum:i8254ED4079B41949
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06027068 Genomic DNA. No translation available.
AY621355 mRNA. Translation: AAT51894.1.
AY600148 mRNA. Translation: AAU04552.1.
CH474050 Genomic DNA. Translation: EDL86062.1.
RefSeqiNP_001032597.1. NM_001037508.1.
UniGeneiRn.147317.

Genome annotation databases

EnsembliENSRNOT00000055408; ENSRNOP00000052276; ENSRNOG00000036897.
GeneIDi641632.
KEGGirno:641632.
UCSCiRGD:1559541. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06027068 Genomic DNA. No translation available.
AY621355 mRNA. Translation: AAT51894.1 .
AY600148 mRNA. Translation: AAU04552.1 .
CH474050 Genomic DNA. Translation: EDL86062.1 .
RefSeqi NP_001032597.1. NM_001037508.1.
UniGenei Rn.147317.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000052276.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000055408 ; ENSRNOP00000052276 ; ENSRNOG00000036897 .
GeneIDi 641632.
KEGGi rno:641632.
UCSCi RGD:1559541. rat.

Organism-specific databases

CTDi 641632.
RGDi 1559541. Defb24.

Phylogenomic databases

eggNOGi NOG87541.
GeneTreei ENSGT00510000050451.
HOGENOMi HOG000112157.
HOVERGENi HBG107794.
InParanoidi Q32ZG8.
OMAi VEDNTNW.
OrthoDBi EOG7DZ8NX.

Miscellaneous databases

NextBioi 714766.
PROi Q32ZG8.

Gene expression databases

Genevestigatori Q32ZG8.

Family and domain databases

InterProi IPR025933. Beta_defensin.
[Graphical view ]
Pfami PF13841. Defensin_beta_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. "Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract."
    Patil A.A., Cai Y., Sang Y., Blecha F., Zhang G.
    Physiol. Genomics 23:5-17(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. "Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus)."
    Yenugu S., Chintalgattu V., Wingard C.J., Radhakrishnan Y., French F.S., Hall S.H.
    Reprod. Biol. Endocrinol. 4:7-7(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WImported.
    Tissue: EpididymisImported.
  6. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ32ZG8_RAT
AccessioniPrimary (citable) accession number: Q32ZG8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: September 3, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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