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Q32RS0 (ODPB_STAPU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismStaurastrum punctulatum (Green alga)
Taxonomic identifier102822 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaZygnemophyceaeDesmidialesDesmidiaceaeStaurastrum

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 328328Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280104

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q32RS0 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 3E88A78FC2BB8F6F

FASTA32835,943
        10         20         30         40         50         60 
MSEMLLFEAL REGLQEEMDR DPKVLVMGED VGHYGGSYKV TKGFAEKYGD LRLLDTPIAE 

        70         80         90        100        110        120 
NSFTGMAIGA AMTGLRPVVE GMNMGFLLLA FNQIANNAGM LHYTSGANFT IPIVIRGPGG 

       130        140        150        160        170        180 
VGRQLGAEHS QRLESYFQSV PGLQLVACST PINAKGLIKS SIRSENPVIL FEHVLLYNLK 

       190        200        210        220        230        240 
ETIPDNEYLV CLEKAEIVRP GTDITILTYS RMRHHVLQAT KSLVYKGYDP EIIDIVSLKP 

       250        260        270        280        290        300 
VDLGTISTSI KKTHKVLIVE ECMRTGGIGA SLRATIMEHL FDFLDAPIMC LSSQDVPTPY 

       310        320 
SGPLEELTVI QPAQIVQAVE QLCNNGNN 

« Hide

References

[1]"The complete chloroplast DNA sequences of the charophycean green algae Staurastrum and Zygnema reveal that the chloroplast genome underwent extensive changes during the evolution of the Zygnematales."
Turmel M., Otis C., Lemieux C.
BMC Biol. 3:22-22(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY958085 Genomic DNA. Translation: AAX45708.1.
RefSeqYP_636456.1. NC_008116.1.

3D structure databases

ProteinModelPortalQ32RS0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4108657.

Phylogenomic databases

ProtClustDBCHL00144.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
InterProIPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_STAPU
AccessionPrimary (citable) accession number: Q32RS0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: December 6, 2005
Last modified: October 16, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program