Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q32RM2

- ODPB_ZYGCR

UniProt

Q32RM2 - ODPB_ZYGCR

Protein

Pyruvate dehydrogenase E1 component subunit beta

Gene

pdhB

Organism
Zygnema circumcarinatum (Green alga)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 2 (06 Mar 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.By similarity

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei60 – 601Thiamine pyrophosphateBy similarity

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Pyruvate, Thiamine pyrophosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 component subunit beta (EC:1.2.4.1)
    Gene namesi
    Name:pdhB
    Synonyms:odpB
    Encoded oniPlastid; Chloroplast
    OrganismiZygnema circumcarinatum (Green alga)
    Taxonomic identifieri35869 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaZygnemophyceaeZygnematalesZygnemataceaeZygnema

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 325325Pyruvate dehydrogenase E1 component subunit betaPRO_0000280105Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta chain.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ32RM2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProiIPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view]
    PfamiPF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view]
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q32RM2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEVLLFEAL RQGLQEEMDR DPRVMVMGED VGHYGGSYKV TKGFAERYGD    50
    LRLLDTPIAE NSFTGMAIGA AMTGLRPVVE GMNMGFLLLA FNQIANNAGM 100
    LHYTSGGNFT IPIVIRGPGG VGRQLGAEHS QRLESYFQSV PGLQMVACST 150
    PYNAKGLIKS AIRSDNPIIL FEHVLLYNLK EDLAEEEYLV CLEKAEVVRP 200
    GNDITILTYS RMRHNVLQAT KSLVYKGYDP EIIDIVSLKP FDLGTIGASV 250
    CKTHKVLIVE ECMRTGGIGA TLRAAIMEHF FDYLDAPILC LSSQDVPTPY 300
    SSPLEELTVI QPNQIIQVVE QLCEN 325
    Length:325
    Mass (Da):35,808
    Last modified:March 6, 2007 - v2
    Checksum:i0FF32E1811E40420
    GO

    Sequence cautioni

    The sequence AAX45823.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY958086 Genomic DNA. Translation: AAX45823.1. Different initiation.
    RefSeqiYP_636504.1. NC_008117.1.

    Genome annotation databases

    GeneIDi4108143.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY958086 Genomic DNA. Translation: AAX45823.1 . Different initiation.
    RefSeqi YP_636504.1. NC_008117.1.

    3D structure databases

    ProteinModelPortali Q32RM2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4108143.

    Family and domain databases

    Gene3Di 3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProi IPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view ]
    Pfami PF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view ]
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete chloroplast DNA sequences of the charophycean green algae Staurastrum and Zygnema reveal that the chloroplast genome underwent extensive changes during the evolution of the Zygnematales."
      Turmel M., Otis C., Lemieux C.
      BMC Biol. 3:22-22(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiODPB_ZYGCR
    AccessioniPrimary (citable) accession number: Q32RM2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 6, 2007
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 40 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program