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Q32RM2 (ODPB_ZYGCR) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta
EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismZygnema circumcarinatum (Green alga)
Taxonomic identifier35869 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Zygnemophyceae › Zygnematales › Zygnemataceae › Zygnema

Protein attributes

Sequence length325 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastid › chloroplast.

Sequence caution

The sequence AAX45823.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 325325Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280105

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q32RM2 [UniParc].

Last modified March 6, 2007. Version 2.
Checksum: 0FF32E1811E40420

FASTA32535,808
        10         20         30         40         50         60 
MAEVLLFEAL RQGLQEEMDR DPRVMVMGED VGHYGGSYKV TKGFAERYGD LRLLDTPIAE 

        70         80         90        100        110        120 
NSFTGMAIGA AMTGLRPVVE GMNMGFLLLA FNQIANNAGM LHYTSGGNFT IPIVIRGPGG 

       130        140        150        160        170        180 
VGRQLGAEHS QRLESYFQSV PGLQMVACST PYNAKGLIKS AIRSDNPIIL FEHVLLYNLK 

       190        200        210        220        230        240 
EDLAEEEYLV CLEKAEVVRP GNDITILTYS RMRHNVLQAT KSLVYKGYDP EIIDIVSLKP 

       250        260        270        280        290        300 
FDLGTIGASV CKTHKVLIVE ECMRTGGIGA TLRAAIMEHF FDYLDAPILC LSSQDVPTPY 

       310        320 
SSPLEELTVI QPNQIIQVVE QLCEN

« Hide

References

[1]"The complete chloroplast DNA sequences of the charophycean green algae Staurastrum and Zygnema reveal that the chloroplast genome underwent extensive changes during the evolution of the Zygnematales."
Turmel M., Otis C., Lemieux C.
BMC Biol. 3:22-22(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY958086 Genomic DNA. Translation: AAX45823.1. Different initiation.
RefSeqYP_636504.1. NC_008117.1.

3D structure databases

HSSPHSSP built from PDB template 2BFF based on UniProtKB P21953.
ProteinModelPortalQ32RM2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4108143.

Phylogenomic databases

ProtClustDBCHL00144.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
InterProIPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_ZYGCR
AccessionPrimary (citable) accession number: Q32RM2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: March 6, 2007
Last modified: March 6, 2013
This is version 35 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
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