ID   Q32PZ5_RAT              Unreviewed;       493 AA.
AC   Q32PZ5;
DT   06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT   06-DEC-2005, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Ctr9 protein {ECO:0000313|EMBL:AAI07917.1};
DE   Flags: Fragment;
GN   Name=Ctr9 {ECO:0000313|EMBL:AAI07917.1, ECO:0000313|RGD:1311097};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|EMBL:AAI07917.1};
RN   [1] {ECO:0000313|EMBL:AAI07917.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta {ECO:0000313|EMBL:AAI07917.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC107916; AAI07917.1; -; mRNA.
DR   AlphaFoldDB; Q32PZ5; -.
DR   UCSC; RGD:1311097; rat.
DR   AGR; RGD:1311097; -.
DR   RGD; 1311097; Ctr9.
DR   PhylomeDB; Q32PZ5; -.
DR   GO; GO:0016593; C:Cdc73/Paf1 complex; ISO:RGD.
DR   GO; GO:0000791; C:euchromatin; ISO:RGD.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR   GO; GO:0042169; F:SH2 domain binding; ISO:RGD.
DR   GO; GO:0001832; P:blastocyst growth; ISO:RGD.
DR   GO; GO:0001835; P:blastocyst hatching; ISO:RGD.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISO:RGD.
DR   GO; GO:0006325; P:chromatin organization; ISO:RGD.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISO:RGD.
DR   GO; GO:0001826; P:inner cell mass cell differentiation; ISO:RGD.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; ISO:RGD.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; ISO:RGD.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISO:RGD.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; ISO:RGD.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:RGD.
DR   GO; GO:0007259; P:receptor signaling pathway via JAK-STAT; ISO:RGD.
DR   GO; GO:0019827; P:stem cell population maintenance; ISO:RGD.
DR   GO; GO:0006368; P:transcription elongation by RNA polymerase II; ISO:RGD.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; ISO:RGD.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR031101; Ctr9.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR14027; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9; 1.
DR   PANTHER; PTHR14027:SF2; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT   REGION          212..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          148..205
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        215..239
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..277
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..325
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..419
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        420..444
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        459..475
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..493
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAI07917.1"
SQ   SEQUENCE   493 AA;  55534 MW;  045234A8C7056A83 CRC64;
     SDVWLNLAHI YVEQKQYISA VQMYENCLRK FYKHQNTEVV LYLARALFKC GKLQECKQTL
     LKARHVAPSD TVLMFNVALV LQRLATSVLK DEKSNLKEVL NAVKELELAH RYFSYLSKVG
     DKMRFDLALA ASEARQCSDL LSQAQYHVAR ARKQDEEERE LRAKQEQEKE LLRQKLLKEQ
     EEKRLREKEE QKKLLEQRAQ YVEKTKNILM FTGETEATKE KKRGGGGGRR SKKGGEFDEF
     VNDDTDDDLP ISKKKKKRKG SGSEQEGEEE EGGERKKKRR RRPPKGEEGS DDDETENGPK
     PKKRRPPRAE KKKAPKPERL PPSMKGKIKS KAIISSSDDS SDEDKLKIAD EGHPRNSNSD
     SDDDERPNRR ASSESDSDDN QNKSGSEAGS PRRSGRQESD EDSDSDQPSR KRRRSGSEQS
     DNESAQSGRS PSGGSENEND SRPVSPSAES DHESEQGSDN EGSGQGSGNE SEPEGSNNEA
     SDRGSEHGSD DSD
//