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Protein

Protein phosphatase 1 regulatory subunit 7

Gene

ppp1r7

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regulatory subunit of protein phosphatase 1.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 7
Alternative name(s):
Protein phosphatase 1 regulatory subunit 22
Gene namesi
Name:ppp1r7
Synonyms:sds22
ORF Names:zgc:123325
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-051113-288. ppp1r7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002396171 – 345Protein phosphatase 1 regulatory subunit 7Add BLAST345

Proteomic databases

PaxDbiQ32PL1.
PRIDEiQ32PL1.

Expressioni

Gene expression databases

BgeeiENSDARG00000009740.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000025441.

Structurei

3D structure databases

ProteinModelPortaliQ32PL1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati62 – 83LRR 1Add BLAST22
Repeati84 – 105LRR 2Add BLAST22
Repeati106 – 127LRR 3Add BLAST22
Repeati128 – 149LRR 4Add BLAST22
Repeati150 – 171LRR 5Add BLAST22
Repeati172 – 193LRR 6Add BLAST22
Repeati194 – 215LRR 7Add BLAST22
Repeati216 – 237LRR 8Add BLAST22
Repeati238 – 259LRR 9Add BLAST22
Repeati260 – 281LRR 10Add BLAST22
Repeati282 – 303LRR 11Add BLAST22
Domaini316 – 345LRRCTAdd BLAST30

Sequence similaritiesi

Belongs to the SDS22 family.Curated
Contains 11 LRR (leucine-rich) repeats.Curated
Contains 1 LRRCT domain.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0531. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00730000110223.
HOGENOMiHOG000211189.
HOVERGENiHBG082161.
InParanoidiQ32PL1.
KOiK17550.
OMAiEELWLNH.
OrthoDBiEOG091G0FWO.
PhylomeDBiQ32PL1.
TreeFamiTF105538.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR003603. U2A'_phosphoprotein32A_C.
[Graphical view]
SMARTiSM00369. LRR_TYP. 6 hits.
SM00446. LRRcap. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q32PL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLSVGEPQ EMEVDRRGES EESGDDETKR KSLNGEVDSL QAPSTVPEES
60 70 80 90 100
PVDMDTITLD PEEEDVDLVH CRIGKIEGLE VLLKAKTISL RQNLIKRIEN
110 120 130 140 150
LESLVSLREL DLYDNQIRKL ENLQALTELE QLDVSFNLLR KIEGLDSLTK
160 170 180 190 200
VKKLFLLHNK IASIANLDHL TSLQMLELGS NRIRVIENLD SLSSLESLFL
210 220 230 240 250
GTNKITQLQN LDGLHNLTVL SIQSNRITKL EGLQNLVNLR ELYLSHNGIE
260 270 280 290 300
VMEGLENNKK LSTLDIAANR IKKIENISHL TDLKEFWMND NQIENWADLD
310 320 330 340
ELKNAKGLET VYLERNPLQK DPQYRRKIML ALPSVRQIDA TFIRF
Length:345
Mass (Da):39,385
Last modified:December 6, 2005 - v1
Checksum:i6EA817ECA7DEDE5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108074 mRNA. Translation: AAI08075.1.
RefSeqiNP_001032463.1. NM_001037386.2.
UniGeneiDr.76971.

Genome annotation databases

EnsembliENSDART00000022356; ENSDARP00000025441; ENSDARG00000009740.
GeneIDi560323.
KEGGidre:560323.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108074 mRNA. Translation: AAI08075.1.
RefSeqiNP_001032463.1. NM_001037386.2.
UniGeneiDr.76971.

3D structure databases

ProteinModelPortaliQ32PL1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000025441.

Proteomic databases

PaxDbiQ32PL1.
PRIDEiQ32PL1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000022356; ENSDARP00000025441; ENSDARG00000009740.
GeneIDi560323.
KEGGidre:560323.

Organism-specific databases

CTDi5510.
ZFINiZDB-GENE-051113-288. ppp1r7.

Phylogenomic databases

eggNOGiKOG0531. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00730000110223.
HOGENOMiHOG000211189.
HOVERGENiHBG082161.
InParanoidiQ32PL1.
KOiK17550.
OMAiEELWLNH.
OrthoDBiEOG091G0FWO.
PhylomeDBiQ32PL1.
TreeFamiTF105538.

Miscellaneous databases

PROiQ32PL1.

Gene expression databases

BgeeiENSDARG00000009740.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR003603. U2A'_phosphoprotein32A_C.
[Graphical view]
SMARTiSM00369. LRR_TYP. 6 hits.
SM00446. LRRcap. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 11 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPP1R7_DANRE
AccessioniPrimary (citable) accession number: Q32PL1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: December 6, 2005
Last modified: October 5, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.