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Protein

39S ribosomal protein L4, mitochondrial

Gene

MRPL4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-BTA-5368286. Mitochondrial translation initiation.
R-BTA-5389840. Mitochondrial translation elongation.
R-BTA-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L4, mitochondrial
Short name:
L4mt
Short name:
MRP-L4
Gene namesi
Name:MRPL4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 7

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 29429439S ribosomal protein L4, mitochondrialPRO_0000238948Add
BLAST

Proteomic databases

PaxDbiQ32PI6.
PRIDEiQ32PI6.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000001861.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FTCelectron microscopy-D97-270[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ32PI6.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L4P family.Curated

Phylogenomic databases

eggNOGiKOG1624. Eukaryota.
COG0088. LUCA.
GeneTreeiENSGT00390000014512.
HOGENOMiHOG000248767.
HOVERGENiHBG083638.
InParanoidiQ32PI6.
KOiK02926.
OMAiQENVEWQ.
OrthoDBiEOG7F512T.
TreeFamiTF313913.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR023574. Ribosomal_L4_dom.
IPR013005. Ribosomal_uL4/L1e.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q32PI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLVRAGAR AWLRPRGCRG LSALTEEAVQ SAEKPEPLAN AGPQAPVLRR
60 70 80 90 100
CELPVPLHRR PVQAWVESLR GYEQERVGLT ELHPDVFSTA PRLDILHQVA
110 120 130 140 150
IWQKNFKRIS YAKTKTRAEV RGGGRKPWQQ KGSGRARHGS IRSPIWRGGG
160 170 180 190 200
VAHGPRGPTS YYYMLPMKVR VQGLKVALTV KLAQDDLHIV DSLELPTTDP
210 220 230 240 250
QYLMELARYR RWGDSVLFVD LEHEDMPQNV VAATSGLKTF NLIPAIGLNV
260 270 280 290
HSMLKHQTLV LTLPTVAFLE EKLLWHDSRY TPLYPFRLPY RDFP
Length:294
Mass (Da):33,371
Last modified:December 6, 2005 - v1
Checksum:i60DA55E75E29B61F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108102 mRNA. Translation: AAI08103.1.
RefSeqiNP_001032527.1. NM_001037450.2.
UniGeneiBt.40442.

Genome annotation databases

EnsembliENSBTAT00000001861; ENSBTAP00000001861; ENSBTAG00000001419.
GeneIDi507154.
KEGGibta:507154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108102 mRNA. Translation: AAI08103.1.
RefSeqiNP_001032527.1. NM_001037450.2.
UniGeneiBt.40442.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FTCelectron microscopy-D97-270[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000001861.

Proteomic databases

PaxDbiQ32PI6.
PRIDEiQ32PI6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000001861; ENSBTAP00000001861; ENSBTAG00000001419.
GeneIDi507154.
KEGGibta:507154.

Organism-specific databases

CTDi51073.

Phylogenomic databases

eggNOGiKOG1624. Eukaryota.
COG0088. LUCA.
GeneTreeiENSGT00390000014512.
HOGENOMiHOG000248767.
HOVERGENiHBG083638.
InParanoidiQ32PI6.
KOiK02926.
OMAiQENVEWQ.
OrthoDBiEOG7F512T.
TreeFamiTF313913.

Enzyme and pathway databases

ReactomeiR-BTA-5368286. Mitochondrial translation initiation.
R-BTA-5389840. Mitochondrial translation elongation.
R-BTA-5419276. Mitochondrial translation termination.

Miscellaneous databases

EvolutionaryTraceiQ32PI6.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR023574. Ribosomal_L4_dom.
IPR013005. Ribosomal_uL4/L1e.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Rumen.
  2. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
    Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
    J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
  3. "The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present."
    Koc E.C., Burkhart W., Blackburn K., Moyer M.B., Schlatzer D.M., Moseley A., Spremulli L.L.
    J. Biol. Chem. 276:43958-43969(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  4. "A structural model for the large subunit of the mammalian mitochondrial ribosome."
    Mears J.A., Sharma M.R., Gutell R.R., McCook A.S., Richardson P.E., Caulfield T.R., Agrawal R.K., Harvey S.C.
    J. Mol. Biol. 358:193-212(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY ELECTRON MICROSCOPY (12 ANGSTROMS), SUBCELLULAR LOCATION.

Entry informationi

Entry nameiRM04_BOVIN
AccessioniPrimary (citable) accession number: Q32PI6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 6, 2005
Last modified: June 8, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.