Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sperm acrosome-associated protein 5

Gene

SPACA5

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei53PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH22. Glycoside Hydrolase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm acrosome-associated protein 5 (EC:3.2.1.17)
Alternative name(s):
Lysozyme-like protein 5
Gene namesi
Name:SPACA5
Synonyms:LYZL5
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000028446919 – 156Sperm acrosome-associated protein 5Add BLAST138

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 144PROSITE-ProRule annotation
Disulfide bondi48 ↔ 132PROSITE-ProRule annotation
Disulfide bondi82 ↔ 97PROSITE-ProRule annotation
Disulfide bondi93 ↔ 111PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ32PD6.

Expressioni

Gene expression databases

BgeeiENSBTAG00000046069.

Structurei

3D structure databases

ProteinModelPortaliQ32PD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 22 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IT6F. Eukaryota.
ENOG4111EG8. LUCA.
GeneTreeiENSGT00550000074398.
HOVERGENiHBG052297.
InParanoidiQ32PD6.
KOiK01185.
OMAiTQNLCHM.
OrthoDBiEOG091G0R9V.
TreeFamiTF324882.

Family and domain databases

CDDicd00119. LYZ1. 1 hit.
InterProiIPR001916. Glyco_hydro_22.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
IPR030064. LYZL5.
[Graphical view]
PANTHERiPTHR11407:SF31. PTHR11407:SF31. 1 hit.
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q32PD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVSGTIVVI LMAANVEAKI YERCDLAKKL EAAGLNGFKG YTIGDWLCMA
60 70 80 90 100
HYESGFDTSF VNHNPDGSSE YGIFQLNSAW WCYNGVTPSE NLCHMDCHEL
110 120 130 140 150
LNRHILDDIM CAKKVVSSES GMSAWDSWNQ HCYGYDLSEW LRGCHMNAKP

NKKIIS
Length:156
Mass (Da):17,580
Last modified:December 6, 2005 - v1
Checksum:i427670D8003EA25E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108157 mRNA. Translation: AAI08158.1.
RefSeqiNP_001035626.1. NM_001040536.2.
UniGeneiBt.50571.

Genome annotation databases

EnsembliENSBTAT00000063388; ENSBTAP00000055963; ENSBTAG00000046069.
GeneIDi517880.
KEGGibta:517880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108157 mRNA. Translation: AAI08158.1.
RefSeqiNP_001035626.1. NM_001040536.2.
UniGeneiBt.50571.

3D structure databases

ProteinModelPortaliQ32PD6.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH22. Glycoside Hydrolase Family 22.

Proteomic databases

PaxDbiQ32PD6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000063388; ENSBTAP00000055963; ENSBTAG00000046069.
GeneIDi517880.
KEGGibta:517880.

Organism-specific databases

CTDi389852.

Phylogenomic databases

eggNOGiENOG410IT6F. Eukaryota.
ENOG4111EG8. LUCA.
GeneTreeiENSGT00550000074398.
HOVERGENiHBG052297.
InParanoidiQ32PD6.
KOiK01185.
OMAiTQNLCHM.
OrthoDBiEOG091G0R9V.
TreeFamiTF324882.

Gene expression databases

BgeeiENSBTAG00000046069.

Family and domain databases

CDDicd00119. LYZ1. 1 hit.
InterProiIPR001916. Glyco_hydro_22.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
IPR030064. LYZL5.
[Graphical view]
PANTHERiPTHR11407:SF31. PTHR11407:SF31. 1 hit.
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLYZL5_BOVIN
AccessioniPrimary (citable) accession number: Q32PD6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 6, 2005
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.