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Q32PD6 (LYZL5_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sperm acrosome-associated protein 5

EC=3.2.1.17
Alternative name(s):
Lysozyme-like protein 5
Gene names
Name:SPACA5
Synonyms:LYZL5
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length156 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the glycosyl hydrolase 22 family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell wall macromolecule catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionlysozyme activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 156138Sperm acrosome-associated protein 5
PRO_0000284469

Sites

Active site531 By similarity

Amino acid modifications

Disulfide bond24 ↔ 144 By similarity
Disulfide bond48 ↔ 132 By similarity
Disulfide bond82 ↔ 97 By similarity
Disulfide bond93 ↔ 111 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q32PD6 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 427670D8003EA25E

FASTA15617,580
        10         20         30         40         50         60 
MQVSGTIVVI LMAANVEAKI YERCDLAKKL EAAGLNGFKG YTIGDWLCMA HYESGFDTSF 

        70         80         90        100        110        120 
VNHNPDGSSE YGIFQLNSAW WCYNGVTPSE NLCHMDCHEL LNRHILDDIM CAKKVVSSES 

       130        140        150 
GMSAWDSWNQ HCYGYDLSEW LRGCHMNAKP NKKIIS 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Liver.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC108157 mRNA. Translation: AAI08158.1.
RefSeqNP_001035626.1. NM_001040536.2.
UniGeneBt.50571.

3D structure databases

ProteinModelPortalQ32PD6.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH22. Glycoside Hydrolase Family 22.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000063388; ENSBTAP00000055963; ENSBTAG00000046069.
GeneID517880.
KEGGbta:517880.

Organism-specific databases

CTD389852.

Phylogenomic databases

GeneTreeENSGT00550000074398.
HOVERGENHBG052297.
KOK01185.
OMATQNLCHM.
OrthoDBEOG7BW0M5.
TreeFamTF324882.

Family and domain databases

InterProIPR001916. Glyco_hydro_22.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view]
PfamPF00062. Lys. 1 hit.
[Graphical view]
PRINTSPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
PROSITEPS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20872529.

Entry information

Entry nameLYZL5_BOVIN
AccessionPrimary (citable) accession number: Q32PD6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 6, 2005
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries