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Q32PD6

- LYZL5_BOVIN

UniProt

Q32PD6 - LYZL5_BOVIN

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Protein

Sperm acrosome-associated protein 5

Gene

SPACA5

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei53 – 531PROSITE-ProRule annotation

GO - Molecular functioni

  1. lysozyme activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall macromolecule catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH22. Glycoside Hydrolase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm acrosome-associated protein 5 (EC:3.2.1.17)
Alternative name(s):
Lysozyme-like protein 5
Gene namesi
Name:SPACA5
Synonyms:LYZL5
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome X

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 156138Sperm acrosome-associated protein 5PRO_0000284469Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi24 ↔ 144PROSITE-ProRule annotation
Disulfide bondi48 ↔ 132PROSITE-ProRule annotation
Disulfide bondi82 ↔ 97PROSITE-ProRule annotation
Disulfide bondi93 ↔ 111PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ32PD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 22 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00550000074398.
HOVERGENiHBG052297.
InParanoidiQ32PD6.
KOiK01185.
OMAiTQNLCHM.
OrthoDBiEOG7BW0M5.
TreeFamiTF324882.

Family and domain databases

InterProiIPR001916. Glyco_hydro_22.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view]
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q32PD6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQVSGTIVVI LMAANVEAKI YERCDLAKKL EAAGLNGFKG YTIGDWLCMA
60 70 80 90 100
HYESGFDTSF VNHNPDGSSE YGIFQLNSAW WCYNGVTPSE NLCHMDCHEL
110 120 130 140 150
LNRHILDDIM CAKKVVSSES GMSAWDSWNQ HCYGYDLSEW LRGCHMNAKP

NKKIIS
Length:156
Mass (Da):17,580
Last modified:December 6, 2005 - v1
Checksum:i427670D8003EA25E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108157 mRNA. Translation: AAI08158.1.
RefSeqiNP_001035626.1. NM_001040536.2.
UniGeneiBt.50571.

Genome annotation databases

EnsembliENSBTAT00000063388; ENSBTAP00000055963; ENSBTAG00000046069.
GeneIDi517880.
KEGGibta:517880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108157 mRNA. Translation: AAI08158.1 .
RefSeqi NP_001035626.1. NM_001040536.2.
UniGenei Bt.50571.

3D structure databases

ProteinModelPortali Q32PD6.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH22. Glycoside Hydrolase Family 22.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000063388 ; ENSBTAP00000055963 ; ENSBTAG00000046069 .
GeneIDi 517880.
KEGGi bta:517880.

Organism-specific databases

CTDi 389852.

Phylogenomic databases

GeneTreei ENSGT00550000074398.
HOVERGENi HBG052297.
InParanoidi Q32PD6.
KOi K01185.
OMAi TQNLCHM.
OrthoDBi EOG7BW0M5.
TreeFami TF324882.

Miscellaneous databases

NextBioi 20872529.

Family and domain databases

InterProi IPR001916. Glyco_hydro_22.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view ]
Pfami PF00062. Lys. 1 hit.
[Graphical view ]
PRINTSi PR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTi SM00263. LYZ1. 1 hit.
[Graphical view ]
SUPFAMi SSF53955. SSF53955. 1 hit.
PROSITEi PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Liver.

Entry informationi

Entry nameiLYZL5_BOVIN
AccessioniPrimary (citable) accession number: Q32PD6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 6, 2005
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3