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Q32PD6

- LYZL5_BOVIN

UniProt

Q32PD6 - LYZL5_BOVIN

Protein

Sperm acrosome-associated protein 5

Gene

SPACA5

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Catalytic activityi

    Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei53 – 531PROSITE-ProRule annotation

    GO - Molecular functioni

    1. lysozyme activity Source: UniProtKB-EC

    GO - Biological processi

    1. cell wall macromolecule catabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Protein family/group databases

    CAZyiGH22. Glycoside Hydrolase Family 22.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sperm acrosome-associated protein 5 (EC:3.2.1.17)
    Alternative name(s):
    Lysozyme-like protein 5
    Gene namesi
    Name:SPACA5
    Synonyms:LYZL5
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome X

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 156138Sperm acrosome-associated protein 5PRO_0000284469Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi24 ↔ 144PROSITE-ProRule annotation
    Disulfide bondi48 ↔ 132PROSITE-ProRule annotation
    Disulfide bondi82 ↔ 97PROSITE-ProRule annotation
    Disulfide bondi93 ↔ 111PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Structurei

    3D structure databases

    ProteinModelPortaliQ32PD6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 22 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    GeneTreeiENSGT00550000074398.
    HOVERGENiHBG052297.
    KOiK01185.
    OMAiTQNLCHM.
    OrthoDBiEOG7BW0M5.
    TreeFamiTF324882.

    Family and domain databases

    InterProiIPR001916. Glyco_hydro_22.
    IPR000974. Glyco_hydro_22_lys.
    IPR023346. Lysozyme-like_dom.
    [Graphical view]
    PfamiPF00062. Lys. 1 hit.
    [Graphical view]
    PRINTSiPR00137. LYSOZYME.
    PR00135. LYZLACT.
    SMARTiSM00263. LYZ1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53955. SSF53955. 1 hit.
    PROSITEiPS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q32PD6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVSGTIVVI LMAANVEAKI YERCDLAKKL EAAGLNGFKG YTIGDWLCMA    50
    HYESGFDTSF VNHNPDGSSE YGIFQLNSAW WCYNGVTPSE NLCHMDCHEL 100
    LNRHILDDIM CAKKVVSSES GMSAWDSWNQ HCYGYDLSEW LRGCHMNAKP 150
    NKKIIS 156
    Length:156
    Mass (Da):17,580
    Last modified:December 6, 2005 - v1
    Checksum:i427670D8003EA25E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC108157 mRNA. Translation: AAI08158.1.
    RefSeqiNP_001035626.1. NM_001040536.2.
    UniGeneiBt.50571.

    Genome annotation databases

    EnsembliENSBTAT00000063388; ENSBTAP00000055963; ENSBTAG00000046069.
    GeneIDi517880.
    KEGGibta:517880.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC108157 mRNA. Translation: AAI08158.1 .
    RefSeqi NP_001035626.1. NM_001040536.2.
    UniGenei Bt.50571.

    3D structure databases

    ProteinModelPortali Q32PD6.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH22. Glycoside Hydrolase Family 22.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000063388 ; ENSBTAP00000055963 ; ENSBTAG00000046069 .
    GeneIDi 517880.
    KEGGi bta:517880.

    Organism-specific databases

    CTDi 389852.

    Phylogenomic databases

    GeneTreei ENSGT00550000074398.
    HOVERGENi HBG052297.
    KOi K01185.
    OMAi TQNLCHM.
    OrthoDBi EOG7BW0M5.
    TreeFami TF324882.

    Miscellaneous databases

    NextBioi 20872529.

    Family and domain databases

    InterProi IPR001916. Glyco_hydro_22.
    IPR000974. Glyco_hydro_22_lys.
    IPR023346. Lysozyme-like_dom.
    [Graphical view ]
    Pfami PF00062. Lys. 1 hit.
    [Graphical view ]
    PRINTSi PR00137. LYSOZYME.
    PR00135. LYZLACT.
    SMARTi SM00263. LYZ1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53955. SSF53955. 1 hit.
    PROSITEi PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Crossbred X Angus.
      Tissue: Liver.

    Entry informationi

    Entry nameiLYZL5_BOVIN
    AccessioniPrimary (citable) accession number: Q32PD6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 17, 2007
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3