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Protein
Submitted name:

Keratin 5

Gene

Krt5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin 5Imported
Gene namesi
Name:Krt5Imported
ORF Names:mCG_144997Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96702 Krt5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation, KeratinImported

PTM / Processingi

Proteomic databases

PRIDEiQ32P04

Expressioni

Gene expression databases

BgeeiENSMUSG00000061527
ExpressionAtlasiQ32P04 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ32P04
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 475IF rodInterPro annotationAdd BLAST314

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili166 – 186Sequence analysisAdd BLAST21
Coiled coili231 – 265Sequence analysisAdd BLAST35
Coiled coili273 – 293Sequence analysisAdd BLAST21
Coiled coili373 – 460Sequence analysisAdd BLAST88

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IG4R Eukaryota
ENOG410YY6B LUCA
HOVERGENiHBG013015
KOiK07605
OMAiGMRGFSS
OrthoDBiEOG091G09KR

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR032444 Keratin_2_head
IPR003054 Keratin_II
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF16208 Keratin_2_head, 1 hit
PRINTSiPR01276 TYPE2KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q32P04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRQSSVSFR SGGSRSFSAA SAITPSVSRT SFSSVSRSGG GGGGRISLGG
60 70 80 90 100
ACGAGGYGSR SLYNVGGSKR ISYSSGGGSF RNQFGAGGFG FGGGAGSGFG
110 120 130 140 150
FGGGAGSGFG FGGGAGFGGG YGGAGFPVCP PGGIQEVTVN QNLLTPLNLQ
160 170 180 190 200
IDPTIQRVRT EEREQIKTLN NKFASFIDKV RFLEQQNKVL DTKWALLQEQ
210 220 230 240 250
GTKTIKQNLD PLFEQYINNL RRQLDGVLGE RGRLDSELRN MQDLVEDYKN
260 270 280 290 300
KYEDEINKRT TAENEFVMLK KDVDAAYMNK VELEARVDAL MDEINFMKMF
310 320 330 340 350
FDAELSQMQT HVSDTSVVLS MDNNRSLDLD SIIAEVKAQY EDIANRSRTE
360 370 380 390 400
AESWYQTKYE ELQQTAGRHG DDLRNTKHEI SEMNRMIQRL RSEIDNVKKQ
410 420 430 440 450
CANLQNAIAE AEQRGELALK DARNKLTELE EALQKAKQDM ARLLREYQEL
460 470 480 490 500
MNTKLALDVE IATYRKLLEG EECRLSGEGV GPVNISVVTN SVSSGYGGGS
510 520 530 540 550
SIGVGSGFGG GLGSGFAGGL GPRFTRGGGG LGLGSGLSVG GSGFSAGSSQ
560 570 580
GGMSFGSGGG SGSSVKFVST TSSSRRSFKS
Length:580
Mass (Da):61,767
Last modified:April 17, 2007 - v2
Checksum:i304B341FD4224B41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108361 mRNA Translation: AAI08362.2
CH466550 Genomic DNA Translation: EDL04029.1
RefSeqiNP_081287.1, NM_027011.2
UniGeneiMm.451847

Genome annotation databases

GeneIDi110308
KEGGimmu:110308

Similar proteinsi

Entry informationi

Entry nameiQ32P04_MOUSE
AccessioniPrimary (citable) accession number: Q32P04
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: April 17, 2007
Last modified: May 23, 2018
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health