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Protein
Submitted name:

RUNX2 protein

Gene

RUNX2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
RUNX2 proteinImported
Gene namesi
Name:RUNX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 172RuntInterPro annotationAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili31 – 60Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3982 Eukaryota
ENOG4111J4Y LUCA
HOGENOMiHOG000045616
HOVERGENiHBG060268

Family and domain databases

Gene3Di2.60.40.7201 hit
InterProiView protein in InterPro
IPR000040 AML1_Runt
IPR008967 p53-like_TF_DNA-bd
IPR012346 p53/RUNT-type_TF_DNA-bd_sf
IPR013524 Runt_dom
PANTHERiPTHR11950 PTHR11950, 1 hit
PfamiView protein in Pfam
PF00853 Runt, 1 hit
PRINTSiPR00967 ONCOGENEAML1
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS51062 RUNT, 1 hit

Sequencei

Sequence statusi: Complete.

Q32MY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIPVDPSTS RRFSPPSSSL QPGKMSDVSP VVAAQQQQQQ QQQQQQQQQQ
60 70 80 90 100
QQQQQQQEAA AAAAAAAAAV PRLRPPHDNR TMVEIIADHP AELVRTDSPN
110 120 130 140 150
FLCSVLPSHW RCNKTLPVAF KVVALGEVPD GTVVTVMAGN DENYSAELRN
160 170
ASAVMKNQVA RFNDLRFVGR SG
Length:172
Mass (Da):18,809
Last modified:December 6, 2005 - v1
Checksum:iD357C6F204AA46E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC108919 mRNA Translation: AAI08920.1
BC108920 mRNA Translation: AAI08921.1
RefSeqiNP_001265407.1, NM_001278478.1
UniGeneiHs.535845

Genome annotation databases

GeneIDi860

Similar proteinsi

Entry informationi

Entry nameiQ32MY8_HUMAN
AccessioniPrimary (citable) accession number: Q32MY8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.