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Protein
Submitted name:

Thyrotropin releasing hormone receptor

Gene

Trhr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Thyrotropin releasing hormone receptorImported
Submitted name:
Trhr proteinImported
Gene namesi
Name:TrhrImported
ORF Names:mCG_16051Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98824. Trhr.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 50HelicalSequence analysisAdd BLAST25
Transmembranei62 – 80HelicalSequence analysisAdd BLAST19
Transmembranei92 – 109HelicalSequence analysisAdd BLAST18
Transmembranei145 – 163HelicalSequence analysisAdd BLAST19
Transmembranei197 – 219HelicalSequence analysisAdd BLAST23
Transmembranei264 – 280HelicalSequence analysisAdd BLAST17
Transmembranei300 – 323HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000038760.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036320.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 320G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST279

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG007549.
KOiK04282.
OMAiKLCNCKQ.
OrthoDBiEOG091G08BE.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00751. THYROLIBRINR.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q32MS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENDTVSEMN QTELQPQAAV ALEYQVVTIL LVVIICGLGI VGNIMVVLVV
60 70 80 90 100
MRTKHMRTPT NCYLVSLAVA DLMVLVAAGL PNITDSIYGS WVYGYVGCLC
110 120 130 140 150
ITYLQYLGIN ASSCSITAFT IERYIAICHP IKAQFLCTFS RAKKIIIFVW
160 170 180 190 200
AFTSIYCMLW FFLLDLNIST YKNAVVVSCG YKISRNYYSP IYLMDFGVFY
210 220 230 240 250
VVPMILATVL YGFIARILFL NPIPSDPKEN SKMWKNDSIH QNKNLNLNAT
260 270 280 290 300
NRCFNSTVSS RKQVTKMLAV VVILFALLWM PYRTLVVVNS FLSSPFQENW
310 320 330 340 350
FLLFCRICIY LNSAINPVIY NLMSQKFRAA FRKLCNCKQK PTEKAANYSV
360 370 380 390
ALNYSVIKES DRFSTELEDI TVTDTYVSTT KVSFDDTCLA SEN
Length:393
Mass (Da):44,559
Last modified:December 6, 2005 - v1
Checksum:i8739B75D1A0FCCFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109005 mRNA. Translation: AAI09006.1.
BC109006 mRNA. Translation: AAI09007.1.
BC128269 mRNA. Translation: AAI28270.1.
CH466541 Genomic DNA. Translation: EDL08750.1.
RefSeqiNP_038724.1. NM_013696.2.
UniGeneiMm.309350.

Genome annotation databases

GeneIDi22045.
KEGGimmu:22045.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109005 mRNA. Translation: AAI09006.1.
BC109006 mRNA. Translation: AAI09007.1.
BC128269 mRNA. Translation: AAI28270.1.
CH466541 Genomic DNA. Translation: EDL08750.1.
RefSeqiNP_038724.1. NM_013696.2.
UniGeneiMm.309350.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036320.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22045.
KEGGimmu:22045.

Organism-specific databases

CTDi7201.
MGIiMGI:98824. Trhr.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG007549.
KOiK04282.
OMAiKLCNCKQ.
OrthoDBiEOG091G08BE.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038760.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00751. THYROLIBRINR.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ32MS1_MOUSE
AccessioniPrimary (citable) accession number: Q32MS1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.