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Q32MN7

- Q32MN7_HUMAN

UniProt

Q32MN7 - Q32MN7_HUMAN

Protein
Submitted name:

TATA box binding protein

Gene

TBP

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (06 Dec 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: Ensembl

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: InterPro
    2. positive regulation of transcription, DNA-templated Source: Ensembl
    3. spermatogenesis Source: Ensembl
    4. transcription from RNA polymerase III promoter Source: Ensembl
    5. transcription from RNA polymerase II promoter Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    TATA box binding proteinImported
    Submitted name:
    TATA box binding protein, isoform CRA_aImported
    Gene namesi
    Name:TBPImported
    ORF Names:hCG_2029691Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. female pronucleus Source: Ensembl
    3. male pronucleus Source: Ensembl
    4. transcription factor TFIID complex Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36352.

    Structurei

    3D structure databases

    SMRiQ32MN7. Positions 158-337.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG044997.
    KOiK03120.

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    3.30.310.10. 2 hits.
    HAMAPiMF_00408. TATA_bind_prot_arch.
    InterProiIPR011989. ARM-like.
    IPR012295. Beta2_adaptin/TBP_C_dom.
    IPR000814. TBP.
    [Graphical view]
    PANTHERiPTHR10126. PTHR10126. 1 hit.
    PfamiPF00352. TBP. 2 hits.
    [Graphical view]
    PRINTSiPR00686. TIFACTORIID.
    PROSITEiPS00351. TFIID. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q32MN7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDQNNSLPPY AQGLASPQGA MTPGIPIFSP MMPYGTGLTP QPIQNTNSLS    50
    ILEEQQRQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQAVAAAA 100
    VQQSTSQQAT QGTSGQAPQL FHSQTLTTAP LPGTTPLYPS PMTPMTPITP 150
    ATPASESSGI VPQLQNIVST VNLGCKLDLK TIALRARNAE YNPKRFAAVI 200
    MRIREPRTTA LIFSSGKMVC TGAKSEEQSR LAARKYARVV QKLGFPAKFL 250
    DFKIQNMVGS CDVKFPIRLE GLVLTHQQFS SYEPELFPGL IYRMIKPRIV 300
    LLIFVSGKVV LTGAKVRAEI YEAFENIYPI LKGFRKTT 338
    Length:338
    Mass (Da):37,570
    Last modified:December 6, 2005 - v1
    Checksum:iE86EDE3259A236C9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC109053 mRNA. Translation: AAI09054.1.
    BC110341 mRNA. Translation: AAI10342.1.
    CH471051 Genomic DNA. Translation: EAW47418.1.
    CH471051 Genomic DNA. Translation: EAW47419.1.
    RefSeqiNP_003185.1. NM_003194.4.
    UniGeneiHs.590872.

    Genome annotation databases

    GeneIDi6908.
    KEGGihsa:6908.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC109053 mRNA. Translation: AAI09054.1 .
    BC110341 mRNA. Translation: AAI10342.1 .
    CH471051 Genomic DNA. Translation: EAW47418.1 .
    CH471051 Genomic DNA. Translation: EAW47419.1 .
    RefSeqi NP_003185.1. NM_003194.4.
    UniGenei Hs.590872.

    3D structure databases

    SMRi Q32MN7. Positions 158-337.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 6908.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 6908.
    KEGGi hsa:6908.

    Organism-specific databases

    CTDi 6908.
    PharmGKBi PA36352.

    Phylogenomic databases

    HOVERGENi HBG044997.
    KOi K03120.

    Miscellaneous databases

    GenomeRNAii 6908.
    NextBioi 27015.

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    3.30.310.10. 2 hits.
    HAMAPi MF_00408. TATA_bind_prot_arch.
    InterProi IPR011989. ARM-like.
    IPR012295. Beta2_adaptin/TBP_C_dom.
    IPR000814. TBP.
    [Graphical view ]
    PANTHERi PTHR10126. PTHR10126. 1 hit.
    Pfami PF00352. TBP. 2 hits.
    [Graphical view ]
    PRINTSi PR00686. TIFACTORIID.
    PROSITEi PS00351. TFIID. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LungImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ32MN7_HUMAN
    AccessioniPrimary (citable) accession number: Q32MN7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 6, 2005
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.