TLR10 protein - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q32MI7 (Q32MI7_HUMAN)

Last modified November 25, 2008. Version 29. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
TLR10 protein EMBL AAI09113.1

Gene names

Name:

TLR10 EMBL AAI09113.1

Organism

Homo sapiens (Human) EMBL AAI09113.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	811 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 TIR domain. Spearmint SPM004075

Ontologies

Keywords
Domain	Leucine-rich repeat Spearmint SPM000483 Repeat Spearmint SPM000157
Gene Ontology (GO)
Biological process	innate immune response Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro transmembrane receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q32MI7-1 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: E1A9F9736FD7000A
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811

94,561

        10         20         30         40         50         60 
MRLIRNIYIF CSIVMTAEGD APELPEEREL MTNCSNMSLR KVPADLTPAT TTLDLSYNLL 

        70         80         90        100        110        120 
FQLQSSDFHS VSKLRVLILC HNRIQQLDLK TFEFNKELRY LDLSNNRLKS VTWYLLAGLR 

       130        140        150        160        170        180 
YLDLSFNDFD TMPICEEAGN MSHLEILGLS GAKIQKSDFQ KIAHLHLNTV FLGFRTLPHY 

       190        200        210        220        230        240 
EEGSLPILNT TKLHIVLPMD TNFWVLLRDG IKTSKILEMT NIDGKSQFVS YEMQRNLSLE 

       250        260        270        280        290        300 
HAKTSVLLLN KVDLLWDDLF LILQFVWHTS VEHFQIRNVT FGGKAYLDHN SFDYSNTVMR 

       310        320        330        340        350        360 
TIKLEHVHFR VFYIQQDKIY LLLTKMDIEN LTISNAQMPH MLFPNYPTKF QYLNFANNIL 

       370        380        390        400        410        420 
TDELFKRTLQ LPHLKTLILN GNKLETLSLV SCFANNTPLE HLDLSQNLLQ HKNDENCSWP 

       430        440        450        460        470        480 
ETVVNMNLSY NKLSDSVFRC LPKSIQILDL NNNQIQTVPK ETIHLMALRE LNTAFNFLTD 

       490        500        510        520        530        540 
LPGCSHFSRL SVLNIEMNFI LSPSLDFVQS CQEVKTLNAG RNPFRCTCEL KNFIQLETYS 

       550        560        570        580        590        600 
EVMMVGWSDS YTCEYPLNLR GTRLKDVHLH ELSCNTALLI VTIVVIMLVL GLAVAFCCLH 

       610        620        630        640        650        660 
FDLPWYLRML GQCTQTWHRV RKTTQEQLKR NVRFHAFISY SEHDSLWVKN ELIPNLEKED 

       670        680        690        700        710        720 
GSILICLYES YFDPGKSISE NIVSFIEKSY KSIFVLSPNF VQNEWCHYEF YFAHHNLFHE 

       730        740        750        760        770        780 
NSDHIILILL EPIPFYCIPT RYHKLKALLE KKAYLEWPKD RRKCGLFWAN LRAAVNVNVL 

       790        800        810 
ATREMYELQT FTELNEESRG STISLMRTDC L

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI09113.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	BC109112 mRNA. Translation: AAI09113.1.
UniGene	Hs.120551
3D structure databases
SMR	Q32MI7. Positions 628-776.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000174123. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:15634. TLR10.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q32MI7.
Gene expression databases
ArrayExpress	Q32MI7.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR001611. Leu-rich_rpt. IPR000483. LRR_C. IPR000157. Toll-Interleukin_rcpt. IPR017241. Toll-like_receptor. [Graphical view]
Pfam	PF00560. LRR_1. 5 hits. PF01463. LRRCT. 1 hit. PF01582. TIR. 1 hit. [Graphical view]
PIRSF	PIRSF037595. Toll-like_receptor. 1 hit.
PRINTS	PR01537. INTRLKN1R1F. PR00019. LEURICHRPT.
SMART	SM00082. LRRCT. 1 hit. SM00255. TIR. 1 hit. [Graphical view]
PROSITE	PS50104. TIR. 1 hit. [Graphical view]

Entry information

Entry name

Q32MI7_HUMAN

Accession

Primary (citable) accession number: Q32MI7

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	November 25, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information