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Protein

G kinase-anchoring protein 1

Gene

GKAP1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
G kinase-anchoring protein 1
Gene namesi
Name:GKAP1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 8

Organism-specific databases

VGNCiVGNC:29387 GKAP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003156531 – 363G kinase-anchoring protein 1Add BLAST363

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei23PhosphoserineBy similarity1
Modified residuei25PhosphoserineBy similarity1
Modified residuei27PhosphoserineBy similarity1
Modified residuei104Phosphoserine; by PKGBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ32LE2
PRIDEiQ32LE2

Expressioni

Gene expression databases

BgeeiENSBTAG00000023523

Interactioni

Subunit structurei

Interacts with PRKG1.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012912

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili43 – 75Sequence analysisAdd BLAST33
Coiled coili126 – 158Sequence analysisAdd BLAST33
Coiled coili240 – 350Sequence analysisAdd BLAST111

Sequence similaritiesi

Belongs to the GKAP1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IF7C Eukaryota
ENOG410YKPT LUCA
GeneTreeiENSGT00390000008742
HOGENOMiHOG000070157
HOVERGENiHBG107948
InParanoidiQ32LE2
OMAiQGEMKDK
OrthoDBiEOG091G0IVX
TreeFamiTF328459

Family and domain databases

InterProiView protein in InterPro
IPR026109 GKAP1
PANTHERiPTHR14899 PTHR14899, 1 hit
PRINTSiPR02083 GKINASEAP1

Sequencei

Sequence statusi: Complete.

Q32LE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAVLSSVP TTASRFALLQ VDSGSGSDSE PGKGKGRNTG KSQTNKSTTN
60 70 80 90 100
EKKREKRRKK KEQQQSEANE LRNLAFKKIP QKSSHAICNA QHELSLPNPV
110 120 130 140 150
QKDSREENWQ EWRQRDEQLT SEMFEADLEK ALLLSKLEYE EHKKEYENAE
160 170 180 190 200
NASTQSKVMN KKDKRKTHQG KDKPLTISLK EFQSEDHISK KTEELSSQIL
210 220 230 240 250
SHDGGFFNRL EDDVHKILTR EKRREQLTEY NGTDNYTVHE HNQEVVLKDG
260 270 280 290 300
RIERLKLELE RKDAEIQKLK NVIAQWEAKY KEVKARNAQL LKMLQEGEMK
310 320 330 340 350
DKAEILLQVD ESQSIKNELT IQVTSLHAAL EQERSKVKVL QAELAKYQGG
360
RKGKRNSESD QCR
Length:363
Mass (Da):41,881
Last modified:January 15, 2008 - v2
Checksum:i368D6EBE6FA940EB
GO

Sequence cautioni

The sequence AAI09626 differs from that shown. Reason: Frameshift at positions 173 and 242.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109625 mRNA Translation: AAI09626.1 Frameshift.
RefSeqiNP_001035663.2, NM_001040573.3
UniGeneiBt.63572

Genome annotation databases

EnsembliENSBTAT00000012912; ENSBTAP00000012912; ENSBTAG00000023523
GeneIDi613960
KEGGibta:613960

Similar proteinsi

Entry informationi

Entry nameiGKAP1_BOVIN
AccessioniPrimary (citable) accession number: Q32LE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: March 28, 2018
This is version 65 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health