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Protein

G kinase-anchoring protein 1

Gene

GKAP1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
G kinase-anchoring protein 1
Gene namesi
Name:GKAP1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136 Componenti: Chromosome 8

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 363363G kinase-anchoring protein 1PRO_0000315653Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei27 – 271PhosphoserineBy similarity
Modified residuei104 – 1041Phosphoserine; by PKGBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ32LE2.

Interactioni

Subunit structurei

Interacts with PRKG1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012912.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili43 – 7533Sequence AnalysisAdd
BLAST
Coiled coili126 – 15833Sequence AnalysisAdd
BLAST
Coiled coili240 – 350111Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the GKAP1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG299603.
GeneTreeiENSGT00390000008742.
HOGENOMiHOG000070157.
HOVERGENiHBG107948.
InParanoidiQ32LE2.
OMAiQQGEMKD.
OrthoDBiEOG7GJ6D6.
TreeFamiTF328459.

Family and domain databases

InterProiIPR026109. GKAP1.
[Graphical view]
PANTHERiPTHR14899. PTHR14899. 1 hit.
PRINTSiPR02083. GKINASEAP1.

Sequencei

Sequence statusi: Complete.

Q32LE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAVLSSVP TTASRFALLQ VDSGSGSDSE PGKGKGRNTG KSQTNKSTTN
60 70 80 90 100
EKKREKRRKK KEQQQSEANE LRNLAFKKIP QKSSHAICNA QHELSLPNPV
110 120 130 140 150
QKDSREENWQ EWRQRDEQLT SEMFEADLEK ALLLSKLEYE EHKKEYENAE
160 170 180 190 200
NASTQSKVMN KKDKRKTHQG KDKPLTISLK EFQSEDHISK KTEELSSQIL
210 220 230 240 250
SHDGGFFNRL EDDVHKILTR EKRREQLTEY NGTDNYTVHE HNQEVVLKDG
260 270 280 290 300
RIERLKLELE RKDAEIQKLK NVIAQWEAKY KEVKARNAQL LKMLQEGEMK
310 320 330 340 350
DKAEILLQVD ESQSIKNELT IQVTSLHAAL EQERSKVKVL QAELAKYQGG
360
RKGKRNSESD QCR
Length:363
Mass (Da):41,881
Last modified:January 15, 2008 - v2
Checksum:i368D6EBE6FA940EB
GO

Sequence cautioni

The sequence AAI09626.1 differs from that shown. Reason: Frameshift at positions 173 and 242. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109625 mRNA. Translation: AAI09626.1. Frameshift.
RefSeqiNP_001035663.2. NM_001040573.2.
XP_005210406.1. XM_005210349.2.
UniGeneiBt.63572.

Genome annotation databases

EnsembliENSBTAT00000012912; ENSBTAP00000012912; ENSBTAG00000023523.
GeneIDi613960.
KEGGibta:613960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109625 mRNA. Translation: AAI09626.1. Frameshift.
RefSeqiNP_001035663.2. NM_001040573.2.
XP_005210406.1. XM_005210349.2.
UniGeneiBt.63572.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012912.

Proteomic databases

PRIDEiQ32LE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000012912; ENSBTAP00000012912; ENSBTAG00000023523.
GeneIDi613960.
KEGGibta:613960.

Organism-specific databases

CTDi80318.

Phylogenomic databases

eggNOGiNOG299603.
GeneTreeiENSGT00390000008742.
HOGENOMiHOG000070157.
HOVERGENiHBG107948.
InParanoidiQ32LE2.
OMAiQQGEMKD.
OrthoDBiEOG7GJ6D6.
TreeFamiTF328459.

Miscellaneous databases

NextBioi20898860.

Family and domain databases

InterProiIPR026109. GKAP1.
[Graphical view]
PANTHERiPTHR14899. PTHR14899. 1 hit.
PRINTSiPR02083. GKINASEAP1.
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Liver.

Entry informationi

Entry nameiGKAP1_BOVIN
AccessioniPrimary (citable) accession number: Q32LE2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: March 4, 2015
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.