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Q32LC1 (RPP38_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein subunit p38

Short name=RNaseP protein p38
EC=3.1.26.5
Gene names
Name:RPP38
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus By similarity.

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Subunit structure

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RPP38 is probably a dimer By similarity.

Subcellular location

Nucleusnucleolus Potential.

Sequence similarities

Belongs to the ribosomal protein L7Ae family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
   PTMAcetylation
Phosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 282281Ribonuclease P protein subunit p38
PRO_0000254030

Amino acid modifications

Modified residue21N-acetylalanine By similarity
Modified residue2261Phosphoserine By similarity
Modified residue2351Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q32LC1 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: CC95672164BAD9F5

FASTA28231,413
        10         20         30         40         50         60 
MAAAPQAPGR GSVRKTRPLP VKTSLNNPYS ICWGVLDRED MHFILQTLED RIQSLGLQKI 

        70         80         90        100        110        120 
EDRKRKKKQP PLKKQSGDTS SIDVDTGEDL KKEKPKGDAQ ASGWTPVDVR KQLAIGINEV 

       130        140        150        160        170        180 
TRALERNELL LALACKSAKP AIVTSHLVQL SVSRGVRACQ VPRLSERLAP VLGLKCVLAL 

       190        200        210        220        230        240 
GFKRNTTAFG EELRAILPRV PRLNVAWLQD ALEDPRENLQ TESLESQDEE ILDTSFEDLS 

       250        260        270        280 
KPKRKLAEGQ QPVVLQPLKI KKLIPNPNKI RKPPKSKRTA SK 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Liver.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC109652 mRNA. Translation: AAI09653.1.
RefSeqNP_001033174.1. NM_001038085.2.
UniGeneBt.24490.

3D structure databases

ProteinModelPortalQ32LC1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000010127.

Proteomic databases

PRIDEQ32LC1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID511723.
KEGGbta:511723.

Organism-specific databases

CTD10557.

Phylogenomic databases

eggNOGNOG308103.
HOGENOMHOG000231566.
HOVERGENHBG060241.
InParanoidQ32LC1.
KOK14523.

Family and domain databases

Gene3D3.30.1330.30. 1 hit.
InterProIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
[Graphical view]
PfamPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
SUPFAMSSF55315. SSF55315. 1 hit.
ProtoNetSearch...

Other

NextBio20870066.

Entry information

Entry nameRPP38_BOVIN
AccessionPrimary (citable) accession number: Q32LC1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 6, 2005
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries