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Q32KZ1 (IF3M_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3, mitochondrial

Short name=IF-3(Mt)
Short name=IF-3Mt
Short name=IF3(mt)
Short name=IF3mt
Gene names
Name:MTIF3
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins By similarity.

Subcellular location

Mitochondrion Probable.

Sequence similarities

Belongs to the IF-3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3232Mitochondrion By similarity
Propeptide33 – 9260Removed in mature form By similarity
PRO_0000280034
Chain93 – 273181Translation initiation factor IF-3, mitochondrial
PRO_0000280035

Regions

Compositional bias62 – 654Poly-Lys

Sequences

Sequence LengthMass (Da)Tools
Q32KZ1 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: FA50E18C558875BF

FASTA27330,619
        10         20         30         40         50         60 
MAALFLKKLT LQTVKTENYC IRRCLGKYIL QGPAPTQQPP RPSCLIHAKA FSTEDTQDEM 

        70         80         90        100        110        120 
TKKKKNETAF SSVGRKINER IIHVLDEQGN DLGHMHRANV IRLMAERDLR LVKRDASAEP 

       130        140        150        160        170        180 
PQYQLLTGAQ IHQERLRLRE AERAAPKPGP TLTKELTFSS NIGQHDLDTK SKQIQQWIEK 

       190        200        210        220        230        240 
KYKVQITVKK GKSADEPEDK MEEMCNRIVQ TMSGIATFSS RPQPIRGGKA VMCVLRPLSK 

       250        260        270 
KEEAAWKAAP DTPRRDALNG GDGKDGASGV LPQ 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Liver.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC109845 mRNA. Translation: AAI09846.1.
RefSeqNP_001033155.1. NM_001038066.2.
XP_005213827.1. XM_005213770.1.
XP_005213828.1. XM_005213771.1.
XP_005213829.1. XM_005213772.1.
XP_005213830.1. XM_005213773.1.
UniGeneBt.30788.

3D structure databases

ProteinModelPortalQ32KZ1.
SMRQ32KZ1. Positions 144-245.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000027352.

Proteomic databases

PRIDEQ32KZ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000027352; ENSBTAP00000027352; ENSBTAG00000020530.
GeneID509987.
KEGGbta:509987.

Organism-specific databases

CTD219402.

Phylogenomic databases

eggNOGNOG87881.
GeneTreeENSGT00390000014424.
HOGENOMHOG000264227.
HOVERGENHBG080563.
InParanoidQ32KZ1.
KOK02520.
OMAQTMPGIA.
OrthoDBEOG7DZ8KV.
TreeFamTF332326.

Family and domain databases

Gene3D3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
InterProIPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERPTHR10938. PTHR10938. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
ProtoNetSearch...

Other

NextBio20869232.

Entry information

Entry nameIF3M_BOVIN
AccessionPrimary (citable) accession number: Q32KZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: December 6, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries