Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q32K58 (CAIA_SHIDS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Crotonobetainyl-CoA dehydrogenase
EC=1.3.99.-
Alternative name(s):
Crotonobetainyl-CoA reductase
Gene names
Name:caiA
Ordered Locus Names:SDY_0061
OrganismShigella dysenteriae serotype 1 (strain Sd197)
Taxonomic identifier300267 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA By similarity. HAMAP MF_01052

Cofactor

FAD By similarity. HAMAP MF_01052

Pathway

Amine and polyamine metabolism; carnitine metabolism. HAMAP MF_01052

Subunit structure

Homotetramer By similarity. HAMAP MF_01052

Sequence similarities

Belongs to the acyl-CoA dehydrogenase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionacyl-CoA dehydrogenase activity

Inferred from electronic annotation. Source: InterPro

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 380380Crotonobetainyl-CoA dehydrogenase HAMAP MF_01052
PRO_1000064352

Sequences

Sequence LengthMass (Da)Tools
Q32K58 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 7076984D735652C3

FASTA38042,558
        10         20         30         40         50         60 
MDFNLNDEQE LFVAGIRELM ASENWEAYFA ECDRDSVYPE RFVKALADMG IDSLLIPEEH 

        70         80         90        100        110        120 
GGLDAGFVTL AAVWMELGRL GAPTYVLYQL PGGFNTFLRE GTQEQIDKIM AFRGTGKQMW 

       130        140        150        160        170        180 
NSAITEPGAG SDVGSLKTTY TRRNGKIYLN GSKCFITSSA YTPYIVVMAR DGASPDKPVY 

       190        200        210        220        230        240 
TEWFVDMSKP GIKVTKLEKL GLRMDSCCEI TFDDVELDEK DMFGREGNGF NRVKEEFDHE 

       250        260        270        280        290        300 
RFLVALTNYG TAMCAFEDAA RYANQRVQFG EAIGRFQLIQ EKFAHMAIKL NSMKNMLYEA 

       310        320        330        340        350        360 
AWKADNGTIT SGDAAMCKYF CANAAFEVVD SAMQVLGGVG IAGNHRISRF WRDLRVDRVS 

       370        380 
GGSDEMQILT LGRAVLKQYR

« Hide

References

[1]"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery."
Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. expand/collapse author list , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q.
Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sd197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000034 Genomic DNA. Translation: ABB60299.1.
RefSeqYP_401788.1. NC_007606.1.

3D structure databases

ProteinModelPortalQ32K58.
SMRQ32K58. Positions 5-377.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ32K58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000083269; EBESCP00000080249; EBESCG00000082315.
GeneID3798941.
GenomeReviewsGene locus SDY_0061 in contig CP000034_GR.
KEGGsdy:SDY_0061.
PATRIC18689130. VBIShiDys99784_0067.

Phylogenomic databases

eggNOGCOG1960.
GeneTreeEBGT00050000008857.
HOGENOMHBG699365.
OMAETIGRFQ.
PhylomeDBQ32K58.
ProtClustDBPRK03354.

Enzyme and pathway databases

BioCycSDYS300267:SDY_0061-MONOMER.

Family and domain databases

HAMAPMF_01052. CaiA.
[Tree]
InterProIPR006089. Acyl-CoA_DH_CS.
IPR006092. Acyl-CoA_DH_N.
IPR006090. Acyl-CoA_Oxase/DH_1.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase.
IPR023450. Crotonobetainyl-CoA_DHase_CaiA.
[Graphical view]
Gene3DG3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit.
G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit.
G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 1 hit.
KOK08297.
PfamPF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
[Graphical view]
SUPFAMSSF56645. AcylCoA_dehyd_NM. 1 hit.
SSF47203. AcylCoADH_C_like. 1 hit.
PROSITEPS00072. ACYL_COA_DH_1. 1 hit.
PS00073. ACYL_COA_DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAIA_SHIDS
AccessionPrimary (citable) accession number: Q32K58
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 6, 2005
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents