Q32JF8 (ACPH_SHIDS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative acyl carrier protein phosphodiesterase
Short name=ACP phosphodiesterase
EC=3.1.4.14

Gene names

Name:	acpH
Ordered Locus Names:	SDY_0330

Organism

Shigella dysenteriae serotype 1 (strain Sd197) [Reference proteome] [HAMAP]

Taxonomic identifier

300267 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella › Shigella dysenteriae

Protein attributes

Sequence length	143 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950
Catalytic activity	Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950
Sequence similarities	Belongs to the AcpH family.
Caution	Could be the product of a pseudogene. The N-terminus is shorter than in related proteins.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	[acyl-carrier-protein] phosphodiesterase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 143	143	Putative acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950		PRO_0000226275

Sequences

	Sequence		Length	Mass (Da)
	Q32JF8 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 10319F9D40D95290	FASTA	143	17,464
	10 20 30 40 50 60 MTDNLPEVRE AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM 70 80 90 100 110 120 TILPDSLPRF INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLNAHY 130 140 AALETRFWQF YPRMMAQVSR KAL

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sd197.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000034 Genomic DNA. Translation: ABB60549.1.
RefSeq	YP_402038.1. NC_007606.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	300267.SDY_0330.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABB60549; ABB60549; SDY_0330.
GeneID	3797466.
KEGG	sdy:SDY_0330.
PATRIC	18689780. VBIShiDys99784_0380.
Phylogenomic databases
eggNOG	COG3124.
HOGENOM	HOG000275880.
KO	K08682.
OMA	RIRFANS.
ProtClustDB	CLSK384313.
Enzyme and pathway databases
BioCyc	SDYS300267:GJEW-329-MONOMER.
Family and domain databases
HAMAP	MF_01950. AcpH. Divergent sequence.
InterPro	IPR007431. ACP_phosphodiesterase. [Graphical view]
Pfam	PF04336. DUF479. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACPH_SHIDS

Accession

Primary (citable) accession number: Q32JF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 7, 2006
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program