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Q32EZ9 (6PGL_SHIDS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31
Gene names
Name:pgl
Ordered Locus Names:SDY_2011
OrganismShigella dysenteriae serotype 1 (strain Sd197)
Taxonomic identifier300267 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605

Sequence similarities

Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Glucose metabolism
   Molecular functionHydrolase
   PTMAcetylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3313316-phosphogluconolactonase HAMAP MF_01605
PRO_0000291470

Amino acid modifications

Modified residue2871N6-acetyllysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q32EZ9 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: D731044CFCF31A8F

FASTA33136,308
        10         20         30         40         50         60 
MKQTVYIASP ESQQIHVWNL NHEGALTLTQ VVDVPGQVQP MVVSPDKRYL YVGVRPEFRV 

        70         80         90        100        110        120 
LAYRIAPDDG ALTFAAESAL PGSPTHISTD HQGQFVFVGS YNAGNVSVTR LEDGLPVGVV 

       130        140        150        160        170        180 
DVVEGLDGCH SANISPDNRT LWVPALKQDR ICLFTVSDDG HLVAQDPAEV TTVEGAGPRH 

       190        200        210        220        230        240 
MVFHPNEQYA YCVNELNSSV DVWELKDPHG NIECVQTLDM MPENFSDTRW AADIHITPDG 

       250        260        270        280        290        300 
RHLYACDRTA SLITVFSVSE DGSVLSKEGF QPTETQPRGF NVDHSGKYLI AAGQKSHHIS 

       310        320        330 
VYEIVGEQGL LHEKGRYAVG QGPMWVVVNA H

« Hide

References

[1]"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery."
Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. expand/collapse author list , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q.
Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sd197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000034 Genomic DNA. Translation: ABB62106.1.
RefSeqYP_403597.1. NC_007606.1.

3D structure databases

ProteinModelPortalQ32EZ9.
SMRQ32EZ9. Positions 1-331.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ32EZ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000081355; EBESCP00000078335; EBESCG00000080401.
GeneID3799907.
GenomeReviewsGene locus SDY_2011 in contig CP000034_GR.
KEGGsdy:SDY_2011.
PATRIC18693983. VBIShiDys99784_2424.

Phylogenomic databases

eggNOGCOG2706.
GeneTreeEBGT00050000009586.
HOGENOMHBG741123.
OMACINELNS.
PhylomeDBQ32EZ9.
ProtClustDBPRK11028.

Enzyme and pathway databases

BioCycSDYS300267:SDY_2011-MONOMER.

Family and domain databases

HAMAPMF_01605. 6P-gluconolactonase.
[Tree]
InterProIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
Gene3DG3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KOK07404.
PfamPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMSSF50974. N2O_reductase_N. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_SHIDS
AccessionPrimary (citable) accession number: Q32EZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: December 6, 2005
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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