Q32DU5 (GLPB_SHIDS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	SDY_2437

Organism

Shigella dysenteriae serotype 1 (strain Sd197) [Reference proteome] [HAMAP]

Taxonomic identifier

300267 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella › Shigella dysenteriae

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753
Subunit structure	Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycerol catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 419	419	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753		PRO_0000258908

Sequences

	Sequence		Length	Mass (Da)
	Q32DU5 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: D0B172214645EE48	FASTA	419	45,423
	10 20 30 40 50 60 MRFDTVIMGG GLAGLLCGLQ LQKHGLRSAI VTRGQSALHF SSGSLDLLSH LPDGQAVTDI 70 80 90 100 110 120 HSGLESLRQQ APAHPYSLLG PQRVLDLACQ AQALIAKSGA QLQGSVELPH QRITPLGTLR 130 140 150 160 170 180 STWLSSPEVP VWPLPAKKIC VVGISGLMDF QAHLAAASLR ELDLAVETAE IELPELDVLR 190 200 210 220 230 240 NNATEFRAVN IARFLDNEEN WPLLLDALIP VANTCEMILI PACFGLADDK LWRWLNEKLP 250 260 270 280 290 300 CSLMLLPTLP PSVLSIRLQN QLQRQFVRQG GVWMPGDEVK KVTCKNGVVN EIWTRNHADI 310 320 330 340 350 360 PLRPRFAVLA SGSFFSGGLV AERNGIREPI LGLDVLQTAT RGEWYKEDFF APQPWQQFGV 370 380 390 400 410 TTDQTLRPSQ AGQTIENLFA IGSVLGGFDP IAQGCGGGVC AVSALHAAQQ IAQRAGGQQ

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sd197.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000034 Genomic DNA. Translation: ABB62510.1.
RefSeq	YP_404001.1. NC_007606.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	300267.SDY_2437.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABB62510; ABB62510; SDY_2437.
GeneID	3798238.
KEGG	sdy:SDY_2437.
PATRIC	18695023. VBIShiDys99784_2936.
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HOG000278489.
KO	K00112.
OMA	FRSVNIS.
ProtClustDB	PRK05329.
Enzyme and pathway databases
BioCyc	SDYS300267:GJEW-2433-MONOMER.
UniPathway	UPA00618; UER00673.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB.
InterPro	IPR003953. FAD_bind_dom. IPR009158. G3P_DH_GlpB_su. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_SHIDS

Accession

Primary (citable) accession number: Q32DU5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program