glpB

Functionⁱ

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.UniRule annotation

Catalytic activityⁱ

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactorⁱ

FMNUniRule annotation

Pathwayⁱ: glycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:

Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB)

This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

GO - Molecular functionⁱ

sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

Complete GO annotation...

GO - Biological processⁱ

glycerol catabolic process Source: UniProtKB-UniPathway

Complete GO annotation...

Keywordsⁱ

Molecular function	Oxidoreductase
Ligand	Flavoprotein, FMN

Enzyme and pathway databases

UniPathwayⁱ	UPA00618; UER00673.

UniPathwayⁱ

UPA00618; UER00673.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Anaerobic glycerol-3-phosphate dehydrogenase subunit BUniRule annotation (EC:1.1.5.3UniRule annotation) Short name: Anaerobic G-3-P dehydrogenase subunit BUniRule annotation Short name: Anaerobic G3Pdhase BUniRule annotation
Gene namesⁱ	Name:glpBUniRule annotation Ordered Locus Names:SDY_2437
Organismⁱ	Shigella dysenteriae serotype 1 (strain Sd197)
Taxonomic identifierⁱ	300267 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Shigella › Shigella dysenteriae
Proteomesⁱ	UP000002716 Componentⁱ: Chromosome

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000258908	1 – 419	Anaerobic glycerol-3-phosphate dehydrogenase subunit BAdd BLAST		419

Proteomic databases

PRIDEⁱ	Q32DU5.

PRIDEⁱ

Q32DU5.

Interactionⁱ

Subunit structureⁱ

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.UniRule annotation

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.UniRule annotation

Phylogenomic databases

HOGENOMⁱ	HOG000278489.
KEGG Orthology (KO) More...KOⁱ	K00112.
OMAⁱ	VAINAQC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0GYK.

Family and domain databases

Gene3Dⁱ	3.50.50.60. 1 hit.
HAMAPⁱ	MF_00753. Glycerol3P_GlpB. 1 hit.
InterProⁱ	View protein in InterPro IPR003953. FAD-binding_2. IPR023753. FAD/NAD-binding_dom. IPR009158. G3P_DH_GlpB_su.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00890. FAD_binding_2. 1 hit.
PIRSFⁱ	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
SUPFAMⁱ	SSF51905. SSF51905. 3 hits.
TIGRFAMsⁱ	TIGR03378. glycerol3P_GlpB. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q32DU5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRFDTVIMGG GLAGLLCGLQ LQKHGLRSAI VTRGQSALHF SSGSLDLLSH 
        60         70         80         90        100
LPDGQAVTDI HSGLESLRQQ APAHPYSLLG PQRVLDLACQ AQALIAKSGA 
       110        120        130        140        150
QLQGSVELPH QRITPLGTLR STWLSSPEVP VWPLPAKKIC VVGISGLMDF 
       160        170        180        190        200
QAHLAAASLR ELDLAVETAE IELPELDVLR NNATEFRAVN IARFLDNEEN 
       210        220        230        240        250
WPLLLDALIP VANTCEMILI PACFGLADDK LWRWLNEKLP CSLMLLPTLP 
       260        270        280        290        300
PSVLSIRLQN QLQRQFVRQG GVWMPGDEVK KVTCKNGVVN EIWTRNHADI 
       310        320        330        340        350
PLRPRFAVLA SGSFFSGGLV AERNGIREPI LGLDVLQTAT RGEWYKEDFF 
       360        370        380        390        400
APQPWQQFGV TTDQTLRPSQ AGQTIENLFA IGSVLGGFDP IAQGCGGGVC 
       410 
AVSALHAAQQ IAQRAGGQQ

Length:419

Mass (Da):45,423

Last modified:December 6, 2005 - v1

Checksum:ⁱD0B172214645EE48

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000034 Genomic DNA. Translation: ABB62510.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_001209957.1. NC_007606.1. YP_404001.1. NC_007606.1.

Genome annotation databases

EnsemblBacteriaⁱ	ABB62510; ABB62510; SDY_2437.
GeneIDⁱ	3798238.
KEGGⁱ	sdy:SDY_2437.
PATRICⁱ	fig\|300267.13.peg.2936.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000034 Genomic DNA. Translation: ABB62510.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_001209957.1. NC_007606.1. YP_404001.1. NC_007606.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PRIDEⁱ	Q32DU5.

PRIDEⁱ

Q32DU5.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ABB62510; ABB62510; SDY_2437.
GeneIDⁱ	3798238.
KEGGⁱ	sdy:SDY_2437.
PATRICⁱ	fig\|300267.13.peg.2936.

Phylogenomic databases

HOGENOMⁱ	HOG000278489.
KEGG Orthology (KO) More...KOⁱ	K00112.
OMAⁱ	VAINAQC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0GYK.

Enzyme and pathway databases

UniPathwayⁱ	UPA00618; UER00673.

UniPathwayⁱ

UPA00618; UER00673.

Family and domain databases

Gene3Dⁱ	3.50.50.60. 1 hit.
HAMAPⁱ	MF_00753. Glycerol3P_GlpB. 1 hit.
InterProⁱ	View protein in InterPro IPR003953. FAD-binding_2. IPR023753. FAD/NAD-binding_dom. IPR009158. G3P_DH_GlpB_su.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00890. FAD_binding_2. 1 hit.
PIRSFⁱ	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
SUPFAMⁱ	SSF51905. SSF51905. 3 hits.
TIGRFAMsⁱ	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GLPB_SHIDS
Accessionⁱ	Q32DU5Primary (citable) accession number: Q32DU5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
	Last sequence update:	December 6, 2005
	Last modified:	June 7, 2017
	This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

UniProtKB - Q32DU5 (GLPB_SHIDS)

Your basket is currently empty.

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Select a section on the left to see content.

Functionⁱ

Catalytic activityⁱ

Cofactorⁱ

Pathwayⁱ: glycerol degradation via glycerol kinase pathway

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

PTM / Processingⁱ

Molecule processing

Proteomic databases

Interactionⁱ

Subunit structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q32DU5 (GLPB_SHIDS)

Your basket is currently empty.

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

glpB

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: glycerol degradation via glycerol kinase pathway

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

Pathwayⁱ: glycerol degradation via glycerol kinase pathway

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ