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Protein

Glutamate decarboxylase

Gene

gadA

Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSDYS300267:G1G4A-3939-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
Ordered Locus Names:SDY_3532Imported
OrganismiShigella dysenteriae serotype 1 (strain Sd197)Imported
Taxonomic identifieri300267 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002716 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei274N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PRIDEiQ32AZ6

Structurei

3D structure databases

ProteinModelPortaliQ32AZ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228
KOiK01580
OMAiFTTSVYG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit

Sequencei

Sequence statusi: Complete.

Q32AZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFRVLTMAV DLCRLTTRTM NVNAGHERTS KARIIHQIQL IRGITDELYL
60 70 80 90 100
DGNARQNLAT FCQTWDDENV HKFMDLSINK NWIDKEEYPQ SAAIDLRCVN
110 120 130 140 150
MVADLWHAPA PKNGQAVGTN TIGSSEACML GGMAMKWRWR KRMEAAGKPT
160 170 180 190 200
DKPNLVCGPV QICWHKFARY WDVELREIPM RPGQLFMDPK RMIEACDENT
210 220 230 240 250
IGVVPTFGVT YTGNYEFPQP LHDALDKFQA DTGIDIDMHI DAASGGFLAP
260 270 280 290 300
FVAPDIVWDF RLPRVKSISA SGHKFGLAPL GCGWVIWRDE EALPQELVFN
310 320 330 340 350
VDYLGGQIGT FAINFSRPAG QVIAQYYEFL RLGREGYTKV QNASYQVAAY
360 370 380 390 400
LADEIAKLGP YEFICTGRPD EGIPAVCFKL KDGEDPGYTL YNLSERLRLR
410 420 430 440 450
GWQVPAFTLG GEATDIVVMR IMCRRGFEMD FAELLLEDYK ASLKYLSDHP
460
KLQGIAQQNS FKHT
Length:464
Mass (Da):52,401
Last modified:December 6, 2005 - v1
Checksum:i794788AEE7F9A6E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000034 Genomic DNA Translation: ABB63509.1
RefSeqiWP_011378884.1, NC_007606.1
YP_405000.1, NC_007606.1

Genome annotation databases

EnsemblBacteriaiABB63509; ABB63509; SDY_3532
GeneIDi3798133
KEGGisdy:SDY_3532
PATRICifig|300267.13.peg.4187

Similar proteinsi

Entry informationi

Entry nameiQ32AZ6_SHIDS
AccessioniPrimary (citable) accession number: Q32AZ6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: April 25, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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