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Protein

HTH-type transcriptional activator RhaR

Gene

rhaR

Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activates expression of the rhaSR operon in response to L-rhamnose.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi195 – 214H-T-H motifUniRule annotationAdd BLAST20
DNA bindingi244 – 267H-T-H motifUniRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processRhamnose metabolism, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaRUniRule annotation
Alternative name(s):
L-rhamnose operon transcriptional activator RhaRUniRule annotation
Gene namesi
Name:rhaRUniRule annotation
Ordered Locus Names:SDY_3840
OrganismiShigella dysenteriae serotype 1 (strain Sd197)
Taxonomic identifieri300267 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002716 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002927751 – 282HTH-type transcriptional activator RhaRAdd BLAST282

Interactioni

Subunit structurei

Binds DNA as a dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei246Interaction with sigma-70UniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliQ32A71.
SMRiQ32A71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000290513.
KOiK02854.
OrthoDBiPOG091H039M.

Family and domain databases

HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiView protein in InterPro
IPR003313. AraC-bd.
IPR009057. Homeobox-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiView protein in PROSITE
PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q32A71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHQLKLLKD DFFASDQQAV AVADCYPQDV FAEHTHDFCE LVIVWRGNGL
60 70 80 90 100
HVLNDRPYRI TRGDLFYIHA DDKHSYASVN DLVLQNIIYC PERLKLNLDW
110 120 130 140 150
QGAIPGFSVS AGQPHWRLGS MGMAQARQII GQLEHESSQH VPFANEMAEL
160 170 180 190 200
LFGQLVMLLN RHRYTSDSLP PTSSETLLDK LITRLAASLK SPFALDKFCD
210 220 230 240 250
EASCSERVLR QQFRQQTGMT INQYLRQVRV CHAQYLLQHS RLLISDISTE
260 270 280
CGFEDSNYFS VVFTRETGMT PSQWRHLNSQ KD
Length:282
Mass (Da):32,363
Last modified:July 24, 2007 - v2
Checksum:i12930B0107774999
GO

Sequence cautioni

The sequence ABB63784 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000034 Genomic DNA. Translation: ABB63784.1. Different initiation.
RefSeqiYP_405275.1. NC_007606.1.

Genome annotation databases

EnsemblBacteriaiABB63784; ABB63784; SDY_3840.
GeneIDi3798469.
KEGGisdy:SDY_3840.
PATRICifig|300267.13.peg.4535.

Similar proteinsi

Entry informationi

Entry nameiRHAR_SHIDS
AccessioniPrimary (citable) accession number: Q32A71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: July 24, 2007
Last modified: August 30, 2017
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome