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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Shigella boydii serotype 4 (strain Sb227)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:SBO_0697
OrganismiShigella boydii serotype 4 (strain Sb227)
Taxonomic identifieri300268 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000007067 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003499681 – 308Ribosomal RNA large subunit methyltransferase FAdd BLAST308

Structurei

3D structure databases

ProteinModelPortaliQ323Y7
SMRiQ323Y7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218605
KOiK06970

Family and domain databases

HAMAPiMF_01848 23SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR016909 rRNA_lsu_MeTfrase_F
IPR010286 rRNA_lsu_MeTfrase_F-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR13393 PTHR13393, 1 hit
PfamiView protein in Pfam
PF05971 Methyltransf_10, 1 hit
PIRSFiPIRSF029038 Mtase_YbiN_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

Q323Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAQKPGLHP RNRHHSRYDL ATLCQVNPEL RQFLTLTPAG EQSVDFANPL
60 70 80 90 100
AVKALNKALL AHFYAVANWD IPDGFLCPPV PGRADYIHHL ADLLAEASGT
110 120 130 140 150
IPANASILDI GVGANCIYPL IGVHEYGWRF TGSETSSQAL SSAQAIISAN
160 170 180 190 200
PGLNRAIRLR RQKESGAIFN GIIHKNEQYD ATLCNPPFHD SAAAARAGSE
210 220 230 240 250
RKRRNLGLNK DDALNFGGQQ QELWCEGGEV AFIKKMIEES KGFAKQVMWF
260 270 280 290 300
TSLVSRGENL PPLYRALTDV GAVKVVKKEM AQGQKQSRFI AWTFMNDEQR

RRFVNRQR
Length:308
Mass (Da):34,180
Last modified:September 2, 2008 - v2
Checksum:i10D0EA4C2F3E23D3
GO

Sequence cautioni

The sequence ABB65371 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000036 Genomic DNA Translation: ABB65371.1 Different initiation.

Genome annotation databases

EnsemblBacteriaiABB65371; ABB65371; SBO_0697
KEGGisbo:SBO_0697

Similar proteinsi

Entry informationi

Entry nameiRLMF_SHIBS
AccessioniPrimary (citable) accession number: Q323Y7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 25, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health