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Q31XF6

- MUTH_SHIBS

UniProt

Q31XF6 - MUTH_SHIBS

Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Shigella boydii serotype 4 (strain Sb227)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (06 Dec 2005)
      Previous versions | rss
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    Functioni

    Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. endonuclease activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA modification Source: InterPro
    2. DNA repair Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    DNA damage, DNA repair

    Enzyme and pathway databases

    BioCyciSBOY300268:GJFL-2720-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutHUniRule annotation
    Alternative name(s):
    Methyl-directed mismatch repair proteinUniRule annotation
    Gene namesi
    Name:mutHUniRule annotation
    Ordered Locus Names:SBO_2723
    OrganismiShigella boydii serotype 4 (strain Sb227)
    Taxonomic identifieri300268 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
    ProteomesiUP000007067: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229DNA mismatch repair protein MutHPRO_1000046713Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi300268.SBO_2723.

    Structurei

    3D structure databases

    ProteinModelPortaliQ31XF6.
    SMRiQ31XF6. Positions 3-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MutH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3066.
    HOGENOMiHOG000271839.
    KOiK03573.
    OMAiLRPKGAN.
    OrthoDBiEOG6CGCC0.

    Family and domain databases

    Gene3Di3.40.600.10. 1 hit.
    HAMAPiMF_00759. MutH.
    InterProiIPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view]
    PfamiPF02976. MutH. 1 hit.
    [Graphical view]
    SMARTiSM00927. MutH. 1 hit.
    [Graphical view]
    SUPFAMiSSF52980. SSF52980. 1 hit.
    TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q31XF6-1 [UniParc]FASTAAdd to Basket

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    MSQPRPLLSP PETEEQLLAQ AQQLSGYTLG ELAALAGLVT PENLKRDKGW    50
    IGVLLEIWLG ASAGSKPEQD FAALGVELKT IPVDSLGRPL ETTFVCVAPL 100
    TGNSGVTWET SHVRHKLKRV LWIPVEGERS IPLAQRRVGS PLLWTPNEEE 150
    DRQLREDWEE LMDMIVLGQV ERITARHGEY LQIRPKAANA KALTEAIGAR 200
    GERILTLPRG FYLKKNFTSA LLARHFLIQ 229
    Length:229
    Mass (Da):25,513
    Last modified:December 6, 2005 - v1
    Checksum:i27D5CA945B937CB8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000036 Genomic DNA. Translation: ABB67252.1.
    RefSeqiYP_409080.1. NC_007613.1.

    Genome annotation databases

    EnsemblBacteriaiABB67252; ABB67252; SBO_2723.
    GeneIDi3781706.
    KEGGisbo:SBO_2723.
    PATRICi18684914. VBIShiBoy33460_3356.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000036 Genomic DNA. Translation: ABB67252.1 .
    RefSeqi YP_409080.1. NC_007613.1.

    3D structure databases

    ProteinModelPortali Q31XF6.
    SMRi Q31XF6. Positions 3-229.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300268.SBO_2723.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB67252 ; ABB67252 ; SBO_2723 .
    GeneIDi 3781706.
    KEGGi sbo:SBO_2723.
    PATRICi 18684914. VBIShiBoy33460_3356.

    Phylogenomic databases

    eggNOGi COG3066.
    HOGENOMi HOG000271839.
    KOi K03573.
    OMAi LRPKGAN.
    OrthoDBi EOG6CGCC0.

    Enzyme and pathway databases

    BioCyci SBOY300268:GJFL-2720-MONOMER.

    Family and domain databases

    Gene3Di 3.40.600.10. 1 hit.
    HAMAPi MF_00759. MutH.
    InterProi IPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view ]
    Pfami PF02976. MutH. 1 hit.
    [Graphical view ]
    SMARTi SM00927. MutH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52980. SSF52980. 1 hit.
    TIGRFAMsi TIGR02248. mutH_TIGR. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sb227.

    Entry informationi

    Entry nameiMUTH_SHIBS
    AccessioniPrimary (citable) accession number: Q31XF6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3