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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Shigella boydii serotype 4 (strain Sb227)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processDNA damage, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:SBO_2723
OrganismiShigella boydii serotype 4 (strain Sb227)
Taxonomic identifieri300268 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000007067 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000467131 – 229DNA mismatch repair protein MutHAdd BLAST229

Structurei

3D structure databases

ProteinModelPortaliQ31XF6
SMRiQ31XF6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MutH family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000271839
KOiK03573
OMAiPPDLKRD

Family and domain databases

CDDicd00583 MutH_Sau3AI, 1 hit
Gene3Di3.40.600.10, 1 hit
HAMAPiMF_00759 MutH, 1 hit
InterProiView protein in InterPro
IPR004230 DNA_mismatch_repair_MutH
IPR011337 DNA_rep_MutH/RE_typeII
IPR037057 DNA_rep_MutH/RE_typeII_sf
IPR011335 Restrct_endonuc-II-like
PfamiView protein in Pfam
PF02976 MutH, 1 hit
SMARTiView protein in SMART
SM00927 MutH, 1 hit
SUPFAMiSSF52980 SSF52980, 1 hit
TIGRFAMsiTIGR02248 mutH_TIGR, 1 hit

Sequencei

Sequence statusi: Complete.

Q31XF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQPRPLLSP PETEEQLLAQ AQQLSGYTLG ELAALAGLVT PENLKRDKGW
60 70 80 90 100
IGVLLEIWLG ASAGSKPEQD FAALGVELKT IPVDSLGRPL ETTFVCVAPL
110 120 130 140 150
TGNSGVTWET SHVRHKLKRV LWIPVEGERS IPLAQRRVGS PLLWTPNEEE
160 170 180 190 200
DRQLREDWEE LMDMIVLGQV ERITARHGEY LQIRPKAANA KALTEAIGAR
210 220
GERILTLPRG FYLKKNFTSA LLARHFLIQ
Length:229
Mass (Da):25,513
Last modified:December 6, 2005 - v1
Checksum:i27D5CA945B937CB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000036 Genomic DNA Translation: ABB67252.1

Genome annotation databases

EnsemblBacteriaiABB67252; ABB67252; SBO_2723
KEGGisbo:SBO_2723

Similar proteinsi

Entry informationi

Entry nameiMUTH_SHIBS
AccessioniPrimary (citable) accession number: Q31XF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health