Q31U72 (CDH_SHIBS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
CDP-diacylglycerol pyrophosphatase
EC=3.6.1.26

Alternative name(s):
CDP-diacylglycerol phosphatidylhydrolase
CDP-diglyceride hydrolase

Gene names

Name:	cdh
Ordered Locus Names:	SBO_3935

Organism

Shigella boydii serotype 4 (strain Sb227) [Complete proteome] [HAMAP]

Taxonomic identifier

300268 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	251 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	CDP-diacylglycerol + H2O = CMP + phosphatidate. HAMAP MF_00319
Pathway	Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. HAMAP MF_00319
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity HAMAP MF_00319.
Sequence similarities	Belongs to the cdh family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	CDP-diacylglycerol diphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 251	251	CDP-diacylglycerol pyrophosphatase HAMAP MF_00319		PRO_1000019267
Regions
	Transmembrane	4 – 24	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q31U72 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: C987D3A4B12BE5F3	FASTA	251	28,383
	10 20 30 40 50 60 MKKAGLLFLV MIVIAVVAAG IGYWKLTGEE SDTLRKIVLE ECLPNQQQNQ NPSPCAEVKP 70 80 90 100 110 120 NAGYVVLKDL NGPLQYLLMP TYRINGTESP LLTDPSTPNF FWLAWQARDF MSKKYGQPVP 130 140 150 160 170 180 DRAVSLAINS RTGRTQNHFH IHISCIRPDV REQLDNNLAN ISSRWLPLPG GLRGHEYLAR 190 200 210 220 230 240 RVTESELVQR SPFMMLAEEV PEAREHMGSY GLAMVRQSDN SFVLLATQRN LLTLNRASAE 250 EIQDHQCEIL R

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sb227.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000036 Genomic DNA. Translation: ABB68386.1.
RefSeq	YP_410214.1. NC_007613.1.
3D structure databases
ProteinModelPortal	Q31U72.
SMR	Q31U72. Positions 31-250.
ModBase	Search...
Protein-protein interaction databases
STRING	Q31U72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000079296; EBESCP00000076443; EBESCG00000078343.
GeneID	3782918.
GenomeReviews	Gene locus SBO_3935 in contig CP000036_GR.
KEGG	sbo:SBO_3935.
PATRIC	18687716. VBIShiBoy33460_4719.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000011118.
HOGENOM	HBG565233.
OMA	DINGPLQ.
PhylomeDB	Q31U72.
ProtClustDB	PRK05471.
Enzyme and pathway databases
BioCyc	SBOY300268:SBO_3935-MONOMER.
Family and domain databases
HAMAP	MF_00319. Cdh. [Tree]
InterPro	IPR003763. CDP-diacylglyc_Pase. IPR015993. CDP-diacylglyc_Pase_proteobac. [Graphical view]
KO	K01521.
Pfam	PF02611. CDH. 1 hit. [Graphical view]
PIRSF	PIRSF001273. CDH. 1 hit.
TIGRFAMs	TIGR00672. Cdh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CDH_SHIBS

Accession

Primary (citable) accession number: Q31U72

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 6, 2005
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program