Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q31LS2 (UPPP_SYNE7) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Synpcc7942_1967
OrganismSynechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) [Complete proteome] [HAMAP]
Taxonomic identifier1140 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250276

Regions

Transmembrane11 – 3121Helical; Potential
Transmembrane49 – 6921Helical; Potential
Transmembrane94 – 11421Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane199 – 21921Helical; Potential
Transmembrane234 – 25421Helical; Potential
Transmembrane265 – 28521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q31LS2 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 348CDCD918336077

FASTA28830,868
        10         20         30         40         50         60 
MLIAVSSADR LDLWQAIVLG FVQGATEFLP ISSTAHLKVV PVVLGWGDPG VAFTAVIQLG 

        70         80         90        100        110        120 
SIVAVLSYFR QDLTYVLRGL VSAVRRQDFR SEPAQMGLGI LFGTIPILIG GLLIKRFIPD 

       130        140        150        160        170        180 
YDNSPLRSLA AIAIVSIVMG LLLGIAEQLS KHQRDLSQLR LADGLWMGFA QALALIPGVS 

       190        200        210        220        230        240 
RSGSTLTAGL FQGLKRDTAA RFSFLLGIPA ITIAGLVELK DLLEAGIDGS SLGVLAIGTL 

       250        260        270        280 
SSLIFSWLAI AWLLRFLRTH NTWSFVVYRI IFGGVILTAI ATGTLQNI 

« Hide

References

[1]"Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7942.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000100 Genomic DNA. Translation: ABB57997.1.
RefSeqYP_400984.1. NC_007604.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1140.Synpcc7942_1967.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB57997; ABB57997; Synpcc7942_1967.
GeneID3774154.
KEGGsyf:Synpcc7942_1967.
PATRIC23789387. VBISynElo51371_2216.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycSYNEL:SYNPCC7942_1967-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNE7
AccessionPrimary (citable) accession number: Q31LS2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: December 6, 2005
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families