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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Tcr_0198
OrganismiHydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeHydrogenovibrio
Proteomesi
  • UP000002713 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421141 – 592Arginine--tRNA ligaseAdd BLAST592

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi317025.Tcr_0198.

Structurei

3D structure databases

ProteinModelPortaliQ31J79.
SMRiQ31J79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi128 – 138"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31J79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHQVAEILS KVIDQFKQEG VLDASFQPRV NVENTRDKSH GDFATNLAMM
60 70 80 90 100
LTKVVGKPPR EVAEMIVARL PESDVIEKVE IAGPGFINFF VLDVAKFDVL
110 120 130 140 150
PSILEAGETF GECNVGQGRS VLVEYVSANP TGPLHVGHGR GAAYGASVAS
160 170 180 190 200
LLSKAGFRVS REYYVNDAGR QMDILAASTW LRYLQHCGEE LTFPSNGYKG
210 220 230 240 250
DYIFDIAQSL YEEKGDALRK PAENVFEGVA DDEVTTADGE TLGDKEKHID
260 270 280 290 300
DLIEKTKVLL GDEHYRVVFD KALDAILGDI REDLAEFGVE FENWFSERSL
310 320 330 340 350
MDSGVIDAAL EKLQAAGKIY EKKGALWFKS SEYGDEKDRV VVRENGLKTY
360 370 380 390 400
FASDIAYHFN KLERGFDVLI DIWGSDHHGY VPRVKAAMQA LDTNPEALEV
410 420 430 440 450
LLVQFAVLYR GGEKLAMSTR SGQFVTLREL RDEVGADAAR FFYVQRKSEQ
460 470 480 490 500
HMDFDLDLAK SKSNENPVYY IQYAHARICQ VLSLAEERGY QLDTEMGLAN
510 520 530 540 550
LNRLTQEPEA DLATLLAKYP EIIARAALAY EPHQIAYYLK ELAHGLHAYY
560 570 580 590
NSTQFIVEYE PLRNARLTLV VAVRQVLQNG LKLLSVAAPE KM
Length:592
Mass (Da):66,266
Last modified:December 6, 2005 - v1
Checksum:i96D37644360CC2E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA. Translation: ABB40794.1.
RefSeqiWP_011369620.1. NC_007520.2.

Genome annotation databases

EnsemblBacteriaiABB40794; ABB40794; Tcr_0198.
KEGGitcx:Tcr_0198.

Similar proteinsi

Entry informationi

Entry nameiSYR_HYDCU
AccessioniPrimary (citable) accession number: Q31J79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 6, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families