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Protein

NAD(P)H dehydrogenase (quinone)

Gene

Tcr_1010

Organism
Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12NAD(P)UniRule annotation1
Binding sitei99SubstrateUniRule annotation1
Binding sitei135FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15FMNUniRule annotation6
Nucleotide bindingi79 – 81FMNUniRule annotation3
Nucleotide bindingi114 – 120FMNUniRule annotation7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciTCRU317025:G1G4Z-1061-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Tcr_1010
OrganismiHydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeHydrogenovibrio
Proteomesi
  • UP000002713 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002910351 – 201NAD(P)H dehydrogenase (quinone)Add BLAST201

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1010

Structurei

3D structure databases

ProteinModelPortaliQ31GW8
SMRiQ31GW8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 191Flavodoxin-likeUniRule annotationAdd BLAST188

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CS1 Bacteria
COG0655 LUCA
HOGENOMiHOG000030539
KOiK03809
OrthoDBiPOG091H03V0

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q31GW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVLVLYYS MYGHVETMAK AIAEGAGSVE GVEVTIKRVP ELMTDEQAKK
60 70 80 90 100
AGVKLDQSAP IATPSELADY DAIIFGTPTR FGNMCAQMRN FLDQTGGLWA
110 120 130 140 150
GGKLINKVGS VFTSTGTQHG GQETTITSFH TNLFHYGMIV VGVPYSCQEM
160 170 180 190 200
TNMNEITGGT PYGASTLAGG DGSRQPSENE IKIAKCQGVH VAKVAKKQSA

S
Length:201
Mass (Da):21,360
Last modified:December 6, 2005 - v1
Checksum:i032EF7FB065BA91E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA Translation: ABB41605.1
RefSeqiWP_011370432.1, NC_007520.2

Genome annotation databases

EnsemblBacteriaiABB41605; ABB41605; Tcr_1010
KEGGitcx:Tcr_1010

Similar proteinsi

Entry informationi

Entry nameiNQOR_HYDCU
AccessioniPrimary (citable) accession number: Q31GW8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health