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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Tcr_1101

Organism
Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg2+ or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei144SubstrateUniRule annotation1
Sitei254Critical for catalysisUniRule annotation1
Metal bindingi349Magnesium or manganeseUniRule annotation1
Sitei419Critical for catalysisUniRule annotation1
Binding sitei546SubstrateUniRule annotation1
Metal bindingi547Magnesium or manganeseUniRule annotation1
Metal bindingi551Magnesium or manganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTCRU317025:G1G4Z-1154-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Tcr_1101Imported
OrganismiHydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)Imported
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeHydrogenovibrio
Proteomesi
  • UP000002713 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1101

Structurei

3D structure databases

ProteinModelPortaliQ31GM7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni131 – 138Substrate bindingUniRule annotation8

Phylogenomic databases

eggNOGiENOG4105E9K Bacteria
COG2838 LUCA
HOGENOMiHOG000240860
KOiK00031
OrthoDBiPOG091H0B3N

Family and domain databases

InterProiView protein in InterPro
IPR004436 Isocitrate_DH_NADP_mono
PANTHERiPTHR36999 PTHR36999, 1 hit
PfamiView protein in Pfam
PF03971 IDH, 1 hit
PIRSFiPIRSF009407 IDH_monmr, 1 hit
TIGRFAMsiTIGR00178 monomer_idh, 1 hit

Sequencei

Sequence statusi: Complete.

Q31GM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKIIYTLT DEAPALATYS LLPIVEAFTK AAGVSVETRD ISLAGRILAN
60 70 80 90 100
VPDKLSEAQK VGDALTELGN LAKTPEANII KLPNISASVP QLNAAIKELQ
110 120 130 140 150
SQGYDIPDYP ATPQNAEEEK IKAAYAKVLG SAVNPVLREG NSDRRAPTSV
160 170 180 190 200
KNFAKKHPHS MGAWSEDSKS KVAHMTEGDF YGSEKSMTLP EATEFKIEFV
210 220 230 240 250
SESGDIKELK GTAPLQAGEV IDAAVMSQKA LRDFLAKAVA EAKEQGILFS
260 270 280 290 300
IHLKATMMKV SDPIIFGQAV SVFFEDVFKK YADEFKKLGV NPNNGLGDVY
310 320 330 340 350
SKIESLPADK QAEIEASIAK TIEDKADVAM VDSDKGITNL HVPSDVIVDA
360 370 380 390 400
SMPAMIRTSG KMWNKDGQQQ DALAVIPDRC YAGVYQETIN FCKHHGAFDP
410 420 430 440 450
TTMGTVPNVG LMAQKAEEYG SHDKTFQMDN AGTVRVVEPN GNVLLEQTVE
460 470 480 490 500
AGDIFRMCQV KDAPIQDWVK LAVNRARATN TPAVFWLDTN RAHDHQLIEK
510 520 530 540 550
VNHYLLDHDT TGLEIHIMSP EEATRFTLRH VKEGKDVISV TGNVLRDYLT
560 570 580 590 600
DLFPILELGT SAKMLSIVPL MNGGGLFETG AGGSAPKHVQ QFMSENHLRW
610 620 630 640 650
DSLGEFLALA VSLEHLATHF NNPKAQVLAD TLDKATGRFL ENNKSPSRKV
660 670 680 690 700
GEIDNRGSHF YLAMYWAQEL AAQKADAELK ARFEKVADAL TQNEDTIMSE
710 720 730
LNGSQGKSVD IGGYYKFNGE LASQAMRPSA TLNTLIDAV
Length:739
Mass (Da):80,615
Last modified:December 6, 2005 - v1
Checksum:iE52ED0373D36817D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA Translation: ABB41696.1
RefSeqiWP_011370523.1, NC_007520.2

Genome annotation databases

EnsemblBacteriaiABB41696; ABB41696; Tcr_1101
KEGGitcx:Tcr_1101

Similar proteinsi

Entry informationi

Entry nameiQ31GM7_HYDCU
AccessioniPrimary (citable) accession number: Q31GM7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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