Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q31GM7

- Q31GM7_THICR

UniProt

Q31GM7 - Q31GM7_THICR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Tcr_1101

Organism
Thiomicrospira crunogena (strain XCL-2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei144 – 1441SubstrateUniRule annotation
Metal bindingi349 – 3491Magnesium or manganeseUniRule annotation
Sitei419 – 4191Critical for catalysisUniRule annotation
Binding sitei546 – 5461SubstrateUniRule annotation
Metal bindingi547 – 5471Magnesium or manganeseUniRule annotation
Metal bindingi551 – 5511Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTCRU317025:GHE8-1122-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Tcr_1101Imported
OrganismiThiomicrospira crunogena (strain XCL-2)Imported
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThiomicrospira
ProteomesiUP000002713: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1101.

Structurei

3D structure databases

ProteinModelPortaliQ31GM7.
SMRiQ31GM7. Positions 2-736.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni131 – 1388Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiARFDKIK.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31GM7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAKIIYTLT DEAPALATYS LLPIVEAFTK AAGVSVETRD ISLAGRILAN
60 70 80 90 100
VPDKLSEAQK VGDALTELGN LAKTPEANII KLPNISASVP QLNAAIKELQ
110 120 130 140 150
SQGYDIPDYP ATPQNAEEEK IKAAYAKVLG SAVNPVLREG NSDRRAPTSV
160 170 180 190 200
KNFAKKHPHS MGAWSEDSKS KVAHMTEGDF YGSEKSMTLP EATEFKIEFV
210 220 230 240 250
SESGDIKELK GTAPLQAGEV IDAAVMSQKA LRDFLAKAVA EAKEQGILFS
260 270 280 290 300
IHLKATMMKV SDPIIFGQAV SVFFEDVFKK YADEFKKLGV NPNNGLGDVY
310 320 330 340 350
SKIESLPADK QAEIEASIAK TIEDKADVAM VDSDKGITNL HVPSDVIVDA
360 370 380 390 400
SMPAMIRTSG KMWNKDGQQQ DALAVIPDRC YAGVYQETIN FCKHHGAFDP
410 420 430 440 450
TTMGTVPNVG LMAQKAEEYG SHDKTFQMDN AGTVRVVEPN GNVLLEQTVE
460 470 480 490 500
AGDIFRMCQV KDAPIQDWVK LAVNRARATN TPAVFWLDTN RAHDHQLIEK
510 520 530 540 550
VNHYLLDHDT TGLEIHIMSP EEATRFTLRH VKEGKDVISV TGNVLRDYLT
560 570 580 590 600
DLFPILELGT SAKMLSIVPL MNGGGLFETG AGGSAPKHVQ QFMSENHLRW
610 620 630 640 650
DSLGEFLALA VSLEHLATHF NNPKAQVLAD TLDKATGRFL ENNKSPSRKV
660 670 680 690 700
GEIDNRGSHF YLAMYWAQEL AAQKADAELK ARFEKVADAL TQNEDTIMSE
710 720 730
LNGSQGKSVD IGGYYKFNGE LASQAMRPSA TLNTLIDAV
Length:739
Mass (Da):80,615
Last modified:December 6, 2005 - v1
Checksum:iE52ED0373D36817D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA. Translation: ABB41696.1.
RefSeqiWP_011370523.1. NC_007520.2.
YP_391370.1. NC_007520.2.

Genome annotation databases

EnsemblBacteriaiABB41696; ABB41696; Tcr_1101.
GeneIDi3760713.
KEGGitcx:Tcr_1101.
PATRICi23974184. VBIThiCru83387_1147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA. Translation: ABB41696.1 .
RefSeqi WP_011370523.1. NC_007520.2.
YP_391370.1. NC_007520.2.

3D structure databases

ProteinModelPortali Q31GM7.
SMRi Q31GM7. Positions 2-736.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 317025.Tcr_1101.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB41696 ; ABB41696 ; Tcr_1101 .
GeneIDi 3760713.
KEGGi tcx:Tcr_1101.
PATRICi 23974184. VBIThiCru83387_1147.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi ARFDKIK.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci TCRU317025:GHE8-1122-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: XCL-2Imported.

Entry informationi

Entry nameiQ31GM7_THICR
AccessioniPrimary (citable) accession number: Q31GM7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 26, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3