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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciTCRU317025:G1G4Z-1167-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Tcr_1114
OrganismiHydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeHydrogenovibrio
Proteomesi
  • UP000002713 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002581071 – 256Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST256

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1114

Structurei

3D structure databases

ProteinModelPortaliQ31GL4
SMRiQ31GL4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q31GL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPIHQPFW LDSKPVVFPP THLAMTEPDG LLAVGGDLTP EWLLNAYHKG
60 70 80 90 100
IFPWFNEDDP ILWWTPNPRS VLFINSLKVR RSLIKTIRKQ QFTVTLDQQF
110 120 130 140 150
EDVMHQCANI ERHDQDGTWI SEEMLSAYTQ LHKSGHAHSV EVWKDNQLVG
160 170 180 190 200
GLYGVAIGKV FFGESMFSKV PDASKIALVA LCQQLKAWGF RIIDTQMETA
210 220 230 240 250
HLRSLGATLI SREYFESILK QETHKDFAPK PWTLEVDWQA PFLAQPTIKK

QKTTTP
Length:256
Mass (Da):29,339
Last modified:December 6, 2005 - v1
Checksum:i3C26679F53B15F75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA Translation: ABB41709.1
RefSeqiWP_011370536.1, NC_007520.2

Genome annotation databases

EnsemblBacteriaiABB41709; ABB41709; Tcr_1114
KEGGitcx:Tcr_1114

Similar proteinsi

Entry informationi

Entry nameiLFTR_HYDCU
AccessioniPrimary (citable) accession number: Q31GL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health