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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei46NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciTCRU317025:G1G4Z-1178-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Tcr_1125
OrganismiHydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena)
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeHydrogenovibrio
Proteomesi
  • UP000002713 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002293911 – 303tRNA pseudouridine synthase BAdd BLAST303

Proteomic databases

PRIDEiQ31GK3

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1125

Structurei

3D structure databases

ProteinModelPortaliQ31GK3
SMRiQ31GK3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
KOiK03177
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR015240 tRNA_sdUridine_synth_fam1_C
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09157 TruB-C_2, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q31GK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKQWQKID GIVLLNKPEG VTSNGLLQQV RRVYNAKKAG HTGALDPFAT
60 70 80 90 100
GLLPICLGEA TKISGLLLDS DKRYIATLQL GLETDSGDKD GNPLKTIAVP
110 120 130 140 150
ALSKAMLETV FSQFEGDVMQ VPPMYSALKH QGKPLYEYAR KGIHIERAAR
160 170 180 190 200
PIHIYELKLI DFENTVVRFE VLCSKGTYVR TLGEDIAKAL GTVGHLTGLH
210 220 230 240 250
RTQTGALTGD EMATLEEIEL NKDAYLQPLD LPLKHLQAIH LNAKDTDKIL
260 270 280 290 300
HGGKLAVEEP ETLLVRFYDP QQRFIGVGEW QQEKQLLKPK RLFNLNPIGD

DHS
Length:303
Mass (Da):33,664
Last modified:December 6, 2005 - v1
Checksum:iA80D5C5EA52DC20E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000109 Genomic DNA Translation: ABB41720.1
RefSeqiWP_011370547.1, NC_007520.2

Genome annotation databases

EnsemblBacteriaiABB41720; ABB41720; Tcr_1125
KEGGitcx:Tcr_1125

Similar proteinsi

Entry informationi

Entry nameiTRUB_HYDCU
AccessioniPrimary (citable) accession number: Q31GK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health