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Q31G54 (Q31G54_THICR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:Tcr_1274
OrganismThiomicrospira crunogena (strain XCL-2) [Complete proteome] [HAMAP]
Taxonomic identifier317025 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Piscirickettsiaceae › Thiomicrospira

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q31G54 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 8848844982A7DE78

FASTA25627,715
        10         20         30         40         50         60 
MIHSTAIVDP SAKIEEGVEI GAYSIIEADV SIGSGSVIGP HVVISGPTTI GKNNRFYQFC 

        70         80         90        100        110        120 
SIGAAPQDKK YADEPTRLTI GDNNTFRENV TVNRGTAQDR GETTIGNDNW VMAGVHIAHD 

       130        140        150        160        170        180 
CVIGNHAIFA NASALAGHVV VNDWAILGGY TLVHQFCNIG EHSFCGMGSV INQDVPNFVT 

       190        200        210        220        230        240 
VSGNLAGPRG LNVEGLKRRG FDKDQIHLVK KAYRALYRTG YRLEEAIYEI DAINDERDTL 

       250 
GSLVSFLKQS NRGIVR

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000109 Genomic DNA. Translation: ABB41869.1.
RefSeqYP_391543.1. NC_007520.2.

3D structure databases

ProteinModelPortalQ31G54.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ31G54.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3761663.
GenomeReviewsGene locus Tcr_1274 in contig CP000109_GR.
KEGGtcx:Tcr_1274.
NMPDRfig|317025.3.peg.1057.
PATRIC23974566. VBIThiCru83387_1327.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1043.
HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBQ31G54.

Enzyme and pathway databases

BioCycTCRU317025:TCR_1274-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 4 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ31G54_THICR
AccessionPrimary (citable) accession number: Q31G54
Entry history
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info